Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312088643> ?p ?o ?g. }
- W4312088643 endingPage "105847" @default.
- W4312088643 startingPage "105847" @default.
- W4312088643 abstract "Tailoring medical models to the right person or risk subgroups delivered at the right time is important in personalized medicine/prevention initiatives. The CIRCA-CHEM randomized 2x2 crossover pilot trial investigated whether the consumption of fruits/vegetables within a time-restricted daily window would affect urinary biomarkers of exposure to neonicotinoids (6-chloronicotinic acid, 6-CN) and pyrethroids (3-phenoxybenzoic acid, 3-PBA) pesticides, a biomarker of oxidative damage (4-hydroxynonenal, 4-HNE) and the associated urinary NMR metabolome. A statistically significant difference (p < 0.001) in both creatinine-adjusted 6-CN and 3-PBA levels was observed between the two-time dietary intervention windows (morning vs. evening). In the evening intervention period, pesticides biomarker levels were higher compared to the baseline, whereas in the morning period, pesticide levels remained unchanged. Positive associations were observed between pesticides and 4-HNE suggesting a diurnal chrono-window of pesticide toxicity. The discovery of a chronotoxicity window associated with chrono-disrupted metabolism of food contaminants may find use in personalized medicine initiatives." @default.
- W4312088643 created "2023-01-04" @default.
- W4312088643 creator A5001852549 @default.
- W4312088643 creator A5002879948 @default.
- W4312088643 creator A5009137163 @default.
- W4312088643 creator A5010231674 @default.
- W4312088643 creator A5023060120 @default.
- W4312088643 creator A5028088642 @default.
- W4312088643 creator A5059194195 @default.
- W4312088643 date "2023-02-01" @default.
- W4312088643 modified "2023-10-11" @default.
- W4312088643 title "A time differentiated dietary intervention effect on the biomarkers of exposure to pyrethroids and neonicotinoids pesticides" @default.
- W4312088643 cites W1591325684 @default.
- W4312088643 cites W1762028130 @default.
- W4312088643 cites W1856696430 @default.
- W4312088643 cites W193946486 @default.
- W4312088643 cites W1943860407 @default.
- W4312088643 cites W1967263936 @default.
- W4312088643 cites W1974744093 @default.
- W4312088643 cites W1979308463 @default.
- W4312088643 cites W1990420924 @default.
- W4312088643 cites W1992909979 @default.
- W4312088643 cites W1993366989 @default.
- W4312088643 cites W2000329954 @default.
- W4312088643 cites W2001316795 @default.
- W4312088643 cites W2001735863 @default.
- W4312088643 cites W2006565594 @default.
- W4312088643 cites W2015220979 @default.
- W4312088643 cites W2024519961 @default.
- W4312088643 cites W2033723100 @default.
- W4312088643 cites W2049784848 @default.
- W4312088643 cites W2051145352 @default.
- W4312088643 cites W2052667522 @default.
- W4312088643 cites W2056606129 @default.
- W4312088643 cites W2070757384 @default.
- W4312088643 cites W2073007304 @default.
- W4312088643 cites W2074888698 @default.
- W4312088643 cites W2077381451 @default.
- W4312088643 cites W2089169036 @default.
- W4312088643 cites W2089320077 @default.
- W4312088643 cites W2089320370 @default.
- W4312088643 cites W2091251942 @default.
- W4312088643 cites W2106905396 @default.
- W4312088643 cites W2111133148 @default.
- W4312088643 cites W2119233246 @default.
- W4312088643 cites W2120740251 @default.
- W4312088643 cites W2124174369 @default.
- W4312088643 cites W2130448354 @default.
- W4312088643 cites W2141768043 @default.
- W4312088643 cites W2149979963 @default.
- W4312088643 cites W2152486489 @default.
- W4312088643 cites W2153219518 @default.
- W4312088643 cites W2159620123 @default.
- W4312088643 cites W2167537549 @default.
- W4312088643 cites W2168497012 @default.
- W4312088643 cites W2185386534 @default.
- W4312088643 cites W2186849858 @default.
- W4312088643 cites W2286598790 @default.
- W4312088643 cites W2308918641 @default.
- W4312088643 cites W2558734686 @default.
- W4312088643 cites W2605280287 @default.
- W4312088643 cites W2611680186 @default.
- W4312088643 cites W2765547603 @default.
- W4312088643 cites W2771413253 @default.
- W4312088643 cites W2788996259 @default.
- W4312088643 cites W2790173628 @default.
- W4312088643 cites W2799787925 @default.
- W4312088643 cites W2888910796 @default.
- W4312088643 cites W2896530182 @default.
- W4312088643 cites W2947071661 @default.
- W4312088643 cites W2949668662 @default.
- W4312088643 cites W2951771534 @default.
- W4312088643 cites W2962816313 @default.
- W4312088643 cites W2995533068 @default.
- W4312088643 cites W2997452304 @default.
- W4312088643 cites W3006494999 @default.
- W4312088643 cites W3087333967 @default.
- W4312088643 cites W3136458211 @default.
- W4312088643 cites W3149666430 @default.
- W4312088643 cites W3197799900 @default.
- W4312088643 cites W3203392861 @default.
- W4312088643 cites W3217009364 @default.
- W4312088643 cites W4210807637 @default.
- W4312088643 cites W4220986650 @default.
- W4312088643 doi "https://doi.org/10.1016/j.isci.2022.105847" @default.
- W4312088643 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36711241" @default.
- W4312088643 hasPublicationYear "2023" @default.
- W4312088643 type Work @default.
- W4312088643 citedByCount "2" @default.
- W4312088643 countsByYear W43120886432023 @default.
- W4312088643 crossrefType "journal-article" @default.
- W4312088643 hasAuthorship W4312088643A5001852549 @default.
- W4312088643 hasAuthorship W4312088643A5002879948 @default.
- W4312088643 hasAuthorship W4312088643A5009137163 @default.
- W4312088643 hasAuthorship W4312088643A5010231674 @default.
- W4312088643 hasAuthorship W4312088643A5023060120 @default.
- W4312088643 hasAuthorship W4312088643A5028088642 @default.
- W4312088643 hasAuthorship W4312088643A5059194195 @default.