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- W4312092904 endingPage "016019" @default.
- W4312092904 startingPage "016019" @default.
- W4312092904 abstract "Abstract Objective: Flexible Electrocorticography (ECoG) electrode arrays that conform to the cortical surface and record surface field potentials from multiple brain regions provide unique insights into how computations occurring in distributed brain regions mediate behavior. Specialized microfabrication methods are required to produce flexible ECoG devices with high-density electrode arrays. However, these fabrication methods are challenging for scientists without access to cleanroom fabrication equipment. Results: Here we present a fully desktop fabricated flexible graphene ECoG array. First, we synthesized a stable, conductive ink via liquid exfoliation of Graphene in Cyrene. Next, we established a stencil-printing process for patterning the graphene ink via laser-cut stencils on flexible polyimide substrates. Benchtop tests indicate that the graphene electrodes have good conductivity of ∼1.1 × 10 3 S cm −1 , flexibility to maintain their electrical connection under static bending, and electrochemical stability in a 15 d accelerated corrosion test. Chronically implanted graphene ECoG devices remain fully functional for up to 180 d, with average in vivo impedances of 24.72 ± 95.23 kΩ at 1 kHz. The ECoG device can measure spontaneous surface field potentials from mice under awake and anesthetized states and sensory stimulus-evoked responses. Significance: The stencil-printing fabrication process can be used to create Graphene ECoG devices with customized electrode layouts within 24 h using commonly available laboratory equipment." @default.
- W4312092904 created "2023-01-04" @default.
- W4312092904 creator A5006088984 @default.
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- W4312092904 date "2023-01-18" @default.
- W4312092904 modified "2023-10-14" @default.
- W4312092904 title "Fully desktop fabricated flexible graphene electrocorticography (ECoG) arrays" @default.
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- W4312092904 doi "https://doi.org/10.1088/1741-2552/acae08" @default.
- W4312092904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36548995" @default.
- W4312092904 hasPublicationYear "2023" @default.
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