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• W4312094512 endingPage "101706" @default.
• W4312094512 startingPage "101706" @default.
• W4312094512 abstract "Human cytomegalovirus (HCMV) infection exerts broad effects on the immune system. These include the differentiation and persistent expansion of a mature NK cell subset which displays a characteristic phenotypic and functional profile hallmarked by expression of the HLA-E-specific CD94/NKG2C activating receptor. Based on our experience and recent advances in the field, we overview the adaptive features of the NKG2C+ NK cell response, discussing observations and open questions on: (a) the mechanisms and influence of viral and host factors; (b) the existence of other NKG2C- NK cell subsets sharing adaptive features; (c) the development and role of adaptive NKG2C+ NK cells in the response to HCMV in hematopoietic and solid organ transplant patients; (d) their relation with other viral infections, mainly HIV-1; and (e) current perspectives for their use in adoptive immunotherapy of cancer." @default.
• W4312094512 created "2023-01-04" @default.
• W4312094512 creator A5006521329 @default.
• W4312094512 creator A5018424217 @default.
• W4312094512 creator A5044514864 @default.
• W4312094512 creator A5044698710 @default.
• W4312094512 creator A5047246047 @default.
• W4312094512 date "2023-01-01" @default.
• W4312094512 modified "2023-10-16" @default.
• W4312094512 title "Adaptive NK cell response to human cytomegalovirus: Facts and open issues" @default.
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