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- W4312102707 abstract "Abstract Sensory loss (hearing, vision, touch, smell, taste) is common in older adults, with over 2/3 of adults over age 55 experiencing loss in multiple senses. Sensory loss has been consistently linked to dementia and cognitive decline in epidemiologic studies. However, research gaps exist, with some senses having been studied more widely than others. Given differing underlying anatomy and physiology of the senses, the nature of the pathways linking sensory loss to dementia may vary and some have yet to be elucidated. For some, it may be that they are both caused by a common underlying biology (e.g., neurodegeneration). Alternatively, potential causal mechanisms include increased cognitive load, changes brain structure/function, social isolation and/or reduced activity. Additionally, gaps exist in how sensory loss may impact the lived experience of people with dementia. This session will address these research gaps by highlighting the work of outstanding junior investigators in the GSA Sensory Health Interest Group. The association between touch and dementia will be reported, a relationship which hitherto has not been well described. We will present on the relationship between olfaction and white matter integrity in the brain and describe how sensory function predicts levels of Alzheimer’s disease biomarkers over 10 years. We will present evidence for associations between audiometric hearing, structural brain volumes, white matter integrity, and cognitive test performance on speech-in-noise processing and will conclude by describing how hearing loss may impact patient-provider communication among older adults with dementia." @default.
- W4312102707 created "2023-01-04" @default.
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- W4312102707 date "2022-11-01" @default.
- W4312102707 modified "2023-10-18" @default.
- W4312102707 title "SENSORY LOSS AND BRAIN HEALTH: SPOTLIGHTING JUNIOR INVESTIGATORS IN THE SENSORY HEALTH INTEREST GROUP" @default.
- W4312102707 doi "https://doi.org/10.1093/geroni/igac059.602" @default.
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