FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312113381> ?p ?o ?g. }

• W4312113381 endingPage "2201245" @default.
• W4312113381 startingPage "2201245" @default.
• W4312113381 abstract "A genomic classifier for usual interstitial pneumonia (gUIP) has been shown to predict histological UIP with high specificity, increasing diagnostic confidence for idiopathic pulmonary fibrosis (IPF). Whether those with positive gUIP classification exhibit a progressive, IPF-like phenotype remains unknown.A pooled, retrospective analysis of patients who underwent clinically indicated diagnostic bronchoscopy with gUIP testing at seven academic medical centres across the USA was performed. We assessed the association between gUIP classification and 18-month progression-free survival (PFS) using Cox proportional hazards regression. PFS was defined as the time from gUIP testing to death from any cause, lung transplant, ≥10% relative decline in forced vital capacity (FVC) or censoring at the time of last available FVC measure. Longitudinal change in FVC was then compared between gUIP classification groups using a joint regression model.Of 238 consecutive patients who underwent gUIP testing, 192 had available follow-up data and were included in the analysis, including 104 with positive gUIP classification and 88 with negative classification. In multivariable analysis, positive gUIP classification was associated with reduced PFS (hazard ratio 1.58, 95% CI 0.86-2.92; p=0.14), but this did not reach statistical significance. Mean annual change in FVC was -101.8 mL (95% CI -142.7- -60.9 mL; p<0.001) for those with positive gUIP classification and -73.2 mL (95% CI -115.2- -31.1 mL; p<0.001) for those with negative classification (difference 28.7 mL, 95% CI -83.2-25.9 mL; p=0.30).gUIP classification was not associated with differential rates of PFS or longitudinal FVC decline in a multicentre interstitial lung disease cohort undergoing bronchoscopy as part of the diagnostic evaluation." @default.
• W4312113381 created "2023-01-04" @default.
• W4312113381 creator A5000816678 @default.
• W4312113381 creator A5005166792 @default.
• W4312113381 creator A5009091055 @default.
• W4312113381 creator A5015339797 @default.
• W4312113381 creator A5015736770 @default.
• W4312113381 creator A5015989559 @default.
• W4312113381 creator A5023917293 @default.
• W4312113381 creator A5029926958 @default.
• W4312113381 creator A5042444062 @default.
• W4312113381 creator A5053137144 @default.
• W4312113381 creator A5061165005 @default.
• W4312113381 creator A5070504333 @default.
• W4312113381 creator A5074903705 @default.
• W4312113381 creator A5086357675 @default.
• W4312113381 date "2022-12-22" @default.
• W4312113381 modified "2023-10-08" @default.
• W4312113381 title "Interstitial lung disease progression after genomic usual interstitial pneumonia testing" @default.
• W4312113381 cites W1990285594 @default.
• W4312113381 cites W2062006349 @default.
• W4312113381 cites W2091915814 @default.
• W4312113381 cites W2095309945 @default.
• W4312113381 cites W2098305693 @default.
• W4312113381 cites W2106327380 @default.
• W4312113381 cites W2125013258 @default.
• W4312113381 cites W2134547880 @default.
• W4312113381 cites W2138871107 @default.
• W4312113381 cites W2152987559 @default.
• W4312113381 cites W2156807514 @default.
• W4312113381 cites W2157572334 @default.
• W4312113381 cites W2168666423 @default.
• W4312113381 cites W2197347269 @default.
• W4312113381 cites W2341043325 @default.
• W4312113381 cites W2384315652 @default.
• W4312113381 cites W2474839550 @default.
• W4312113381 cites W2547362686 @default.
• W4312113381 cites W2598303606 @default.
• W4312113381 cites W2603167199 @default.
• W4312113381 cites W2661861904 @default.
• W4312113381 cites W2770589251 @default.
• W4312113381 cites W2789754687 @default.
• W4312113381 cites W2889197569 @default.
• W4312113381 cites W2890146673 @default.
• W4312113381 cites W2896189647 @default.
• W4312113381 cites W2930468941 @default.
• W4312113381 cites W2974960379 @default.
• W4312113381 cites W2981171309 @default.
• W4312113381 cites W3015330439 @default.
• W4312113381 cites W3022283327 @default.
• W4312113381 cites W3044046114 @default.
• W4312113381 cites W3046088494 @default.
• W4312113381 cites W3122584685 @default.
• W4312113381 cites W3145332293 @default.
• W4312113381 cites W3208112152 @default.
• W4312113381 cites W4200201914 @default.
• W4312113381 cites W4225403198 @default.
• W4312113381 cites W4232017842 @default.
• W4312113381 doi "https://doi.org/10.1183/13993003.01245-2022" @default.
• W4312113381 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36549706" @default.
• W4312113381 hasPublicationYear "2022" @default.
• W4312113381 type Work @default.
• W4312113381 citedByCount "3" @default.
• W4312113381 countsByYear W43121133812023 @default.
• W4312113381 crossrefType "journal-article" @default.
• W4312113381 hasAuthorship W4312113381A5000816678 @default.
• W4312113381 hasAuthorship W4312113381A5005166792 @default.
• W4312113381 hasAuthorship W4312113381A5009091055 @default.
• W4312113381 hasAuthorship W4312113381A5015339797 @default.
• W4312113381 hasAuthorship W4312113381A5015736770 @default.
• W4312113381 hasAuthorship W4312113381A5015989559 @default.
• W4312113381 hasAuthorship W4312113381A5023917293 @default.
• W4312113381 hasAuthorship W4312113381A5029926958 @default.
• W4312113381 hasAuthorship W4312113381A5042444062 @default.
• W4312113381 hasAuthorship W4312113381A5053137144 @default.
• W4312113381 hasAuthorship W4312113381A5061165005 @default.
• W4312113381 hasAuthorship W4312113381A5070504333 @default.
• W4312113381 hasAuthorship W4312113381A5074903705 @default.
• W4312113381 hasAuthorship W4312113381A5086357675 @default.
• W4312113381 hasBestOaLocation W43121133812 @default.
• W4312113381 hasConcept C126322002 @default.
• W4312113381 hasConcept C151956035 @default.
• W4312113381 hasConcept C165637977 @default.
• W4312113381 hasConcept C167135981 @default.
• W4312113381 hasConcept C207103383 @default.
• W4312113381 hasConcept C2777405647 @default.
• W4312113381 hasConcept C2777543607 @default.
• W4312113381 hasConcept C2777714996 @default.
• W4312113381 hasConcept C2778341716 @default.
• W4312113381 hasConcept C3018587741 @default.
• W4312113381 hasConcept C44249647 @default.
• W4312113381 hasConcept C50382708 @default.
• W4312113381 hasConcept C55520419 @default.
• W4312113381 hasConcept C71924100 @default.
• W4312113381 hasConcept C90924648 @default.
• W4312113381 hasConceptScore W4312113381C126322002 @default.
• W4312113381 hasConceptScore W4312113381C151956035 @default.
• W4312113381 hasConceptScore W4312113381C165637977 @default.

• next