FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312113487> ?p ?o ?g. }

• W4312113487 endingPage "638" @default.
• W4312113487 startingPage "621" @default.
• W4312113487 abstract "Carotenoids are the most abundant lipophilic secondary plant metabolites and their dietary intake has been related to a large number of potential health benefits relevant for humans, including even reduced total mortality. An important feature is their potential to impact oxidative stress and inflammatory pathways, by interacting with transcription factors. For example, they may act as precursors of bioactive derivatives activating nuclear hormone receptor mediated signalling. These bioactive derivatives, originating e.g. from β-carotene, i.e. retinoids / vitamin A, can activate the nuclear hormone receptors RARs (retinoic acid receptors). Due to new analytical insights, various novel metabolic pathways were recently outlined to be mediated via distinct nuclear hormone receptor activating pathways that were predicted and further confirmed. In this article, we describe old and novel metabolic pathways from various carotenoids towards novel ligands of alternative nuclear hormone receptors. However, to fully elucidate these pathways, a larger array of techniques and tools, starting from organic synthesis, lipidomics, reporter models, classical in vitro and in vivo models and further omics-approaches and their statistical evaluation are needed to comprehensively and conclusively study this topic. Thus, we further describe state-of-the-art techniques from A to Ω elucidating carotenoid biological mediated activities and describe in detail required materials and methods needed - in practical protocol form - for the various steps of carotenoid investigations." @default.
• W4312113487 created "2023-01-04" @default.
• W4312113487 creator A5005955072 @default.
• W4312113487 creator A5014308020 @default.
• W4312113487 creator A5037065221 @default.
• W4312113487 creator A5040492606 @default.
• W4312113487 creator A5054475861 @default.
• W4312113487 creator A5059364953 @default.
• W4312113487 creator A5078902926 @default.
• W4312113487 creator A5081220483 @default.
• W4312113487 date "2023-01-01" @default.
• W4312113487 modified "2023-09-30" @default.
• W4312113487 title "State-of-the-art methodological investigation of carotenoid activity and metabolism – from organic synthesis <i>via</i> metabolism to biological activity – exemplified by a novel retinoid signalling pathway" @default.
• W4312113487 cites W1121504489 @default.
• W4312113487 cites W1968267349 @default.
• W4312113487 cites W1969768167 @default.
• W4312113487 cites W1980136706 @default.
• W4312113487 cites W1980169422 @default.
• W4312113487 cites W1984607263 @default.
• W4312113487 cites W1986860084 @default.
• W4312113487 cites W1989658935 @default.
• W4312113487 cites W2003877984 @default.
• W4312113487 cites W2008245372 @default.
• W4312113487 cites W2017578370 @default.
• W4312113487 cites W2021689228 @default.
• W4312113487 cites W2022643689 @default.
• W4312113487 cites W2027451664 @default.
• W4312113487 cites W2027876857 @default.
• W4312113487 cites W2032689382 @default.
• W4312113487 cites W2032689600 @default.
• W4312113487 cites W2035074260 @default.
• W4312113487 cites W2053894359 @default.
• W4312113487 cites W2067063449 @default.
• W4312113487 cites W2079266078 @default.
• W4312113487 cites W2081660555 @default.
• W4312113487 cites W2083180890 @default.
• W4312113487 cites W2084862686 @default.
• W4312113487 cites W2089932287 @default.
• W4312113487 cites W2094063119 @default.
• W4312113487 cites W2096660674 @default.
• W4312113487 cites W2099761180 @default.
• W4312113487 cites W2113535510 @default.
• W4312113487 cites W2116205553 @default.
• W4312113487 cites W2128269822 @default.
• W4312113487 cites W2136643063 @default.
• W4312113487 cites W2138365237 @default.
• W4312113487 cites W2169855425 @default.
• W4312113487 cites W2171264777 @default.
• W4312113487 cites W2172184136 @default.
• W4312113487 cites W2265846640 @default.
• W4312113487 cites W2320527186 @default.
• W4312113487 cites W2346206123 @default.
• W4312113487 cites W2425826656 @default.
• W4312113487 cites W2519847021 @default.
• W4312113487 cites W2566123611 @default.
• W4312113487 cites W2594271344 @default.
• W4312113487 cites W2670990050 @default.
• W4312113487 cites W2759363431 @default.
• W4312113487 cites W2783531945 @default.
• W4312113487 cites W2794834241 @default.
• W4312113487 cites W2800703172 @default.
• W4312113487 cites W2804303455 @default.
• W4312113487 cites W2808464237 @default.
• W4312113487 cites W2883243145 @default.
• W4312113487 cites W2886490300 @default.
• W4312113487 cites W2891477748 @default.
• W4312113487 cites W2902544826 @default.
• W4312113487 cites W2912666599 @default.
• W4312113487 cites W2940676612 @default.
• W4312113487 cites W2942757193 @default.
• W4312113487 cites W2950391072 @default.
• W4312113487 cites W2958063045 @default.
• W4312113487 cites W2960900581 @default.
• W4312113487 cites W2971027121 @default.
• W4312113487 cites W2972166981 @default.
• W4312113487 cites W3012819259 @default.
• W4312113487 cites W3015108424 @default.
• W4312113487 cites W3048361594 @default.
• W4312113487 cites W3101412626 @default.
• W4312113487 cites W3106571717 @default.
• W4312113487 cites W3132686172 @default.
• W4312113487 cites W3157039418 @default.
• W4312113487 cites W3161086475 @default.
• W4312113487 cites W3161155336 @default.
• W4312113487 cites W3164380022 @default.
• W4312113487 cites W3167628029 @default.
• W4312113487 cites W4240284353 @default.
• W4312113487 cites W580370566 @default.
• W4312113487 doi "https://doi.org/10.1039/d2fo02816f" @default.
• W4312113487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36562448" @default.
• W4312113487 hasPublicationYear "2023" @default.
• W4312113487 type Work @default.
• W4312113487 citedByCount "5" @default.
• W4312113487 countsByYear W43121134872023 @default.
• W4312113487 crossrefType "journal-article" @default.
• W4312113487 hasAuthorship W4312113487A5005955072 @default.
• W4312113487 hasAuthorship W4312113487A5014308020 @default.
• W4312113487 hasAuthorship W4312113487A5037065221 @default.

• next