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- W4312113804 abstract "The in vivo applications of anthocyanins are limited by their instability. Nano-encapsulation using amylopectin nanoparticles (APNPs) stabilizes anthocyanins to deliver them to tissues to ameliorate their physiological functions. Herein, rats are fed four Aronia melanocarpa anthocyanins encapsulated with APNPs, and their subsequent distributions and bioactivity in nine tissues are revealed using UHPLC-MS. Among digestive tissues, the concentration of the APNP-protected cyanidin 3-O-arabinoside in the stomach is 134.54% of that of the free anthocyanin, while among non-digestive tissues, the APNP-protected cyanidin 3-O-glucoside concentration in the lungs improved by 125.49%. Concentration maxima double peaks in the liver and kidney arise from different modes of transport. Sustained release of anthocyanins from anthocyanin-APNPs and stable concentration curves suggest controlled delivery, with most APNPs consumed in the digestive system. APNPs did not affect the overall anthocyanin absorption time or tissues. The superoxide dismutase and malondialdehyde concentrations indicate that APNPs enhance the oxidative damage protection in vivo." @default.
- W4312113804 created "2023-01-04" @default.
- W4312113804 creator A5013964825 @default.
- W4312113804 creator A5027475930 @default.
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- W4312113804 date "2022-12-23" @default.
- W4312113804 modified "2023-09-26" @default.
- W4312113804 title "Anthocyanins from <i>Aronia melanocarpa</i> Bound to Amylopectin Nanoparticles: Tissue Distribution and In Vivo Oxidative Damage Protection" @default.
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- W4312113804 doi "https://doi.org/10.1021/acs.jafc.2c06115" @default.
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