Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312114865> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W4312114865 abstract "Abstract Background The differential diagnosis of multiple unexplained bone fractures in a young infant usually includes child abuse or bone disease such as osteogenesis imperfecta. Bone abnormalities can occur in 60–80% of cases with congenital syphilis and may be the sole manifestation. However, this frequent manifestation of this rare disease such as congenital syphilis is frequently disregarded. We describe a case of a young infant with multiple long bone fractures diagnosed with congenital syphilis. Case presentation This 2-month-old male patient was referred to our hospital because of fractures of the ulna and distal radius bilaterally and noisy breathing with the suspicion of osteogenesis imperfecta. After thorough examination, the infant had anemia and a palpable spleen. We performed a screen for congenital infections among other investigations, which revealed positive non-treponemal and treponemal antibodies for syphilis. Hence the diagnosis for Congenital Syphilis was made. We performed a lumbar puncture (LP) which showed mild pleocytosis. The patient was treated with intravenous aqueous penicillin G 200 000 UI/KG per day for 10 days. In addition, a single dose of intramuscular penicillin G benzathine 50 000 UI/KG was given due to the abnormal result of CSF. On follow up admission 6 months later, the new syphilis serology had much improved and the new LP revealed no abnormal findings. Conclusions We present this case report in order to remind of a common manifestation of congenital syphilis, a rare disease which needs to be included in the differential diagnosis of multiple unexplained fractures in early infancy. In our case the fractures were symmetric and bilateral and they were accompanied by anemia and mild hepatosplenomegaly which led to the investigation of congenital syphilis as a possible cause. However, two thirds of infants with congenital syphilis are asymptomatic at birth. All women should have a proper syphilis screening during pregnancy." @default.
- W4312114865 created "2023-01-04" @default.
- W4312114865 creator A5006786132 @default.
- W4312114865 creator A5023840756 @default.
- W4312114865 creator A5076786358 @default.
- W4312114865 creator A5081963465 @default.
- W4312114865 date "2022-12-21" @default.
- W4312114865 modified "2023-10-14" @default.
- W4312114865 title "Congenital syphilis as the cause of multiple bone fractures in a young infant case report" @default.
- W4312114865 cites W1980027907 @default.
- W4312114865 cites W1980642262 @default.
- W4312114865 cites W2011747877 @default.
- W4312114865 cites W2016790693 @default.
- W4312114865 cites W2021801531 @default.
- W4312114865 cites W2031757623 @default.
- W4312114865 cites W2090728986 @default.
- W4312114865 cites W2093447013 @default.
- W4312114865 cites W2100920621 @default.
- W4312114865 cites W2102961476 @default.
- W4312114865 cites W2146030907 @default.
- W4312114865 cites W2149062965 @default.
- W4312114865 cites W2149499493 @default.
- W4312114865 cites W2154226670 @default.
- W4312114865 cites W2155443563 @default.
- W4312114865 cites W2156325601 @default.
- W4312114865 cites W2401173529 @default.
- W4312114865 cites W2408331845 @default.
- W4312114865 cites W2890165475 @default.
- W4312114865 cites W2915737634 @default.
- W4312114865 cites W2917519553 @default.
- W4312114865 cites W2973429404 @default.
- W4312114865 cites W4253318439 @default.
- W4312114865 doi "https://doi.org/10.1186/s12887-022-03789-y" @default.
- W4312114865 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36539748" @default.
- W4312114865 hasPublicationYear "2022" @default.
- W4312114865 type Work @default.
- W4312114865 citedByCount "1" @default.
- W4312114865 countsByYear W43121148652023 @default.
- W4312114865 crossrefType "journal-article" @default.
- W4312114865 hasAuthorship W4312114865A5006786132 @default.
- W4312114865 hasAuthorship W4312114865A5023840756 @default.
- W4312114865 hasAuthorship W4312114865A5076786358 @default.
- W4312114865 hasAuthorship W4312114865A5081963465 @default.
- W4312114865 hasBestOaLocation W43121148651 @default.
- W4312114865 hasConcept C141071460 @default.
- W4312114865 hasConcept C142724271 @default.
- W4312114865 hasConcept C187212893 @default.
- W4312114865 hasConcept C2776983459 @default.
- W4312114865 hasConcept C2777668750 @default.
- W4312114865 hasConcept C2780801072 @default.
- W4312114865 hasConcept C2781232182 @default.
- W4312114865 hasConcept C3013748606 @default.
- W4312114865 hasConcept C512399662 @default.
- W4312114865 hasConcept C71924100 @default.
- W4312114865 hasConceptScore W4312114865C141071460 @default.
- W4312114865 hasConceptScore W4312114865C142724271 @default.
- W4312114865 hasConceptScore W4312114865C187212893 @default.
- W4312114865 hasConceptScore W4312114865C2776983459 @default.
- W4312114865 hasConceptScore W4312114865C2777668750 @default.
- W4312114865 hasConceptScore W4312114865C2780801072 @default.
- W4312114865 hasConceptScore W4312114865C2781232182 @default.
- W4312114865 hasConceptScore W4312114865C3013748606 @default.
- W4312114865 hasConceptScore W4312114865C512399662 @default.
- W4312114865 hasConceptScore W4312114865C71924100 @default.
- W4312114865 hasIssue "1" @default.
- W4312114865 hasLocation W43121148651 @default.
- W4312114865 hasLocation W43121148652 @default.
- W4312114865 hasLocation W43121148653 @default.
- W4312114865 hasLocation W43121148654 @default.
- W4312114865 hasOpenAccess W4312114865 @default.
- W4312114865 hasPrimaryLocation W43121148651 @default.
- W4312114865 hasRelatedWork W2065680184 @default.
- W4312114865 hasRelatedWork W2077839924 @default.
- W4312114865 hasRelatedWork W2098968954 @default.
- W4312114865 hasRelatedWork W2281623154 @default.
- W4312114865 hasRelatedWork W2334714975 @default.
- W4312114865 hasRelatedWork W2351045413 @default.
- W4312114865 hasRelatedWork W2351336687 @default.
- W4312114865 hasRelatedWork W2417687090 @default.
- W4312114865 hasRelatedWork W4385640624 @default.
- W4312114865 hasRelatedWork W80167282 @default.
- W4312114865 hasVolume "22" @default.
- W4312114865 isParatext "false" @default.
- W4312114865 isRetracted "false" @default.
- W4312114865 workType "article" @default.