Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312125268> ?p ?o ?g. }
- W4312125268 endingPage "1143" @default.
- W4312125268 startingPage "1143" @default.
- W4312125268 abstract "Odorant-degrading enzymes (ODEs) are proposed to degrade/inactivate volatile organic compounds (VOCs) on a millisecond timescale. Thus, ODEs play an important role in the insect olfactory system as a reset mechanism. The inhibition of these enzymes could incapacitate the olfactory system and, consequently, disrupt chemical communication, promoting and complementing the integrated pest management strategies. Here, we report two novel aldehyde oxidases, AOX-encoding genes GmelAOX2 and GmelAOX3, though transcriptomic analysis in the greater wax moth, Galleria mellonella. GmelAOX2 was clustered in a clade with ODE function, according to phylogenetic analysis. Likewise, to unravel the profile of volatiles that G. mellonella might face besides the sex pheromone blend, VOCs were trapped from honeycombs and the identification was made by gas chromatography-mass spectrometry. Semi-quantitative RT-PCR showed that GmelAXO2 has a sex-biased expression, and qRT-PCR indicated that both GmelAOX2 and GmelAOX3 have a higher relative expression in male antennae rather than female antennae. A functional assay revealed that antennal extracts had the strongest enzymatic activity against undecanal (4-fold) compared to benzaldehyde (control). Our data suggest that these enzymes have a crucial role in metabolizing sex pheromone compounds as well as plant-derived aldehydes, which are related to honeycombs and the life cycle of G. mellonella." @default.
- W4312125268 created "2023-01-04" @default.
- W4312125268 creator A5025258328 @default.
- W4312125268 creator A5050903145 @default.
- W4312125268 creator A5053016164 @default.
- W4312125268 creator A5063709421 @default.
- W4312125268 creator A5089783712 @default.
- W4312125268 date "2022-12-12" @default.
- W4312125268 modified "2023-10-18" @default.
- W4312125268 title "Characterization of Two Aldehyde Oxidases from the Greater Wax Moth, Galleria mellonella Linnaeus. (Lepidoptera: Pyralidae) with Potential Role as Odorant-Degrading Enzymes" @default.
- W4312125268 cites W1459812111 @default.
- W4312125268 cites W1487070368 @default.
- W4312125268 cites W1527783404 @default.
- W4312125268 cites W1537249640 @default.
- W4312125268 cites W1589857163 @default.
- W4312125268 cites W1639758616 @default.
- W4312125268 cites W1669753640 @default.
- W4312125268 cites W1670146044 @default.
- W4312125268 cites W1882312356 @default.
- W4312125268 cites W1920422837 @default.
- W4312125268 cites W1935521819 @default.
- W4312125268 cites W1964064120 @default.
- W4312125268 cites W1964522797 @default.
- W4312125268 cites W1967759501 @default.
- W4312125268 cites W1968395997 @default.
- W4312125268 cites W1971193630 @default.
- W4312125268 cites W1971746644 @default.
- W4312125268 cites W1972981059 @default.
- W4312125268 cites W1980568727 @default.
- W4312125268 cites W1981770628 @default.
- W4312125268 cites W1982608928 @default.
- W4312125268 cites W1984588686 @default.
- W4312125268 cites W1986648838 @default.
- W4312125268 cites W1991045534 @default.
- W4312125268 cites W1993009001 @default.
- W4312125268 cites W1993567146 @default.
- W4312125268 cites W1994759264 @default.
- W4312125268 cites W1996759692 @default.
- W4312125268 cites W2009079898 @default.
- W4312125268 cites W2013668714 @default.
- W4312125268 cites W2014797220 @default.
- W4312125268 cites W2016947962 @default.
- W4312125268 cites W2017462569 @default.
- W4312125268 cites W2018077792 @default.
- W4312125268 cites W2028554894 @default.
- W4312125268 cites W2031611770 @default.
- W4312125268 cites W2034849909 @default.
- W4312125268 cites W2034911947 @default.
- W4312125268 cites W2035164405 @default.
- W4312125268 cites W2036187255 @default.
- W4312125268 cites W2039258351 @default.
- W4312125268 cites W2041805861 @default.
- W4312125268 cites W2041897541 @default.
- W4312125268 cites W2041983465 @default.
- W4312125268 cites W2042536297 @default.
- W4312125268 cites W2046210987 @default.
- W4312125268 cites W2047900663 @default.
- W4312125268 cites W2054589197 @default.
- W4312125268 cites W2057018771 @default.
- W4312125268 cites W2057653427 @default.
- W4312125268 cites W2058959834 @default.
- W4312125268 cites W2060008281 @default.
- W4312125268 cites W2061373652 @default.
- W4312125268 cites W2065119172 @default.
- W4312125268 cites W2065764848 @default.
- W4312125268 cites W2066346589 @default.
- W4312125268 cites W2067581682 @default.
- W4312125268 cites W2069268526 @default.
- W4312125268 cites W2072080137 @default.
- W4312125268 cites W2074779800 @default.
- W4312125268 cites W2074830661 @default.
- W4312125268 cites W2079879908 @default.
- W4312125268 cites W2081139271 @default.
- W4312125268 cites W2082865411 @default.
- W4312125268 cites W2083294656 @default.
- W4312125268 cites W2083775478 @default.
- W4312125268 cites W2085187600 @default.
- W4312125268 cites W2088295129 @default.
- W4312125268 cites W2088794269 @default.
- W4312125268 cites W2089969483 @default.
- W4312125268 cites W2094077708 @default.
- W4312125268 cites W2094353935 @default.
- W4312125268 cites W2108244474 @default.
- W4312125268 cites W2124929346 @default.
- W4312125268 cites W2127016153 @default.
- W4312125268 cites W2128667329 @default.
- W4312125268 cites W2136191352 @default.
- W4312125268 cites W2158714788 @default.
- W4312125268 cites W2165765171 @default.
- W4312125268 cites W2175666918 @default.
- W4312125268 cites W2227951795 @default.
- W4312125268 cites W2316665915 @default.
- W4312125268 cites W2318023368 @default.
- W4312125268 cites W2320348231 @default.
- W4312125268 cites W2332282186 @default.
- W4312125268 cites W2501432566 @default.
- W4312125268 cites W2589031881 @default.
- W4312125268 cites W2613545412 @default.