Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312125541> ?p ?o ?g. }
- W4312125541 endingPage "1792" @default.
- W4312125541 startingPage "1792" @default.
- W4312125541 abstract "The defense system of freshwater crayfish Procambarus clarkii as a diversified source of bioactive molecules with antimicrobial properties was studied. Antimicrobial activity of two polypeptide-enriched extracts obtained from hemocytes and hemolymph of P. clarkii were assessed against Gram positive (Staphylococcus aureus, Enterococcus faecalis) and Gram negative (Pseudomonas aeruginosa, Escherichia coli) bacteria and toward the yeast Candida albicans. The two peptide fractions showed interesting MIC values (ranging from 11 to 700 μg/mL) against all tested pathogens. Polypeptide-enriched extracts were further investigated using a high-resolution mass spectrometry and database search and 14 novel peptides were identified. Some peptides and their derivatives were chemically synthesized and tested in vitro against the bacterial and yeast pathogens. The analysis identified a synthetic derivative peptide, which showed an interesting antifungal (MIC and MFC equal to 31.2 μg/mL and 62.5 μg/mL, respectively) and antibiofilm (BIC50 equal to 23.2 μg/mL) activities against Candida albicans and a low toxicity in human cells." @default.
- W4312125541 created "2023-01-04" @default.
- W4312125541 creator A5004577981 @default.
- W4312125541 creator A5006199350 @default.
- W4312125541 creator A5006737728 @default.
- W4312125541 creator A5008850752 @default.
- W4312125541 creator A5021489950 @default.
- W4312125541 creator A5024036892 @default.
- W4312125541 creator A5033487698 @default.
- W4312125541 creator A5033880797 @default.
- W4312125541 creator A5048666344 @default.
- W4312125541 creator A5052679643 @default.
- W4312125541 creator A5068868350 @default.
- W4312125541 creator A5076200402 @default.
- W4312125541 creator A5079261441 @default.
- W4312125541 creator A5081266236 @default.
- W4312125541 date "2022-12-10" @default.
- W4312125541 modified "2023-09-27" @default.
- W4312125541 title "A Novel Peptide with Antifungal Activity from Red Swamp Crayfish Procambarus clarkii" @default.
- W4312125541 cites W1004448681 @default.
- W4312125541 cites W1536886974 @default.
- W4312125541 cites W1728413725 @default.
- W4312125541 cites W1982718060 @default.
- W4312125541 cites W1991807082 @default.
- W4312125541 cites W2008532179 @default.
- W4312125541 cites W2010509521 @default.
- W4312125541 cites W2011238756 @default.
- W4312125541 cites W2014274241 @default.
- W4312125541 cites W2021328382 @default.
- W4312125541 cites W2029667189 @default.
- W4312125541 cites W2047399603 @default.
- W4312125541 cites W2048362360 @default.
- W4312125541 cites W2059905270 @default.
- W4312125541 cites W2066609648 @default.
- W4312125541 cites W2081840282 @default.
- W4312125541 cites W2091432870 @default.
- W4312125541 cites W2093175536 @default.
- W4312125541 cites W2128635872 @default.
- W4312125541 cites W2142017096 @default.
- W4312125541 cites W2161605421 @default.
- W4312125541 cites W2168639488 @default.
- W4312125541 cites W2170764510 @default.
- W4312125541 cites W2171268876 @default.
- W4312125541 cites W2175270296 @default.
- W4312125541 cites W2212766700 @default.
- W4312125541 cites W2257520994 @default.
- W4312125541 cites W2309847391 @default.
- W4312125541 cites W2322844633 @default.
- W4312125541 cites W2344689512 @default.
- W4312125541 cites W2398326976 @default.
- W4312125541 cites W2414031100 @default.
- W4312125541 cites W2414600499 @default.
- W4312125541 cites W2464403125 @default.
- W4312125541 cites W2588467130 @default.
- W4312125541 cites W2605235260 @default.
- W4312125541 cites W2789307963 @default.
- W4312125541 cites W2898686259 @default.
- W4312125541 cites W2918224803 @default.
- W4312125541 cites W2937953029 @default.
- W4312125541 cites W2943961808 @default.
- W4312125541 cites W2948261638 @default.
- W4312125541 cites W2982380458 @default.
- W4312125541 cites W2982531295 @default.
- W4312125541 cites W2993030000 @default.
- W4312125541 cites W3011858589 @default.
- W4312125541 cites W3012549233 @default.
- W4312125541 cites W3035124439 @default.
- W4312125541 cites W3037206254 @default.
- W4312125541 cites W3045519908 @default.
- W4312125541 cites W3088074039 @default.
- W4312125541 cites W3096768355 @default.
- W4312125541 cites W3107998850 @default.
- W4312125541 cites W3117518633 @default.
- W4312125541 cites W3155913164 @default.
- W4312125541 cites W3164306434 @default.
- W4312125541 cites W3200510020 @default.
- W4312125541 cites W4200162220 @default.
- W4312125541 cites W4200358990 @default.
- W4312125541 cites W4206770032 @default.
- W4312125541 cites W4220836642 @default.
- W4312125541 cites W4224282457 @default.
- W4312125541 cites W4283360111 @default.
- W4312125541 cites W4285403419 @default.
- W4312125541 cites W4293247451 @default.
- W4312125541 cites W4296004618 @default.
- W4312125541 cites W978901490 @default.
- W4312125541 doi "https://doi.org/10.3390/antibiotics11121792" @default.
- W4312125541 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36551449" @default.
- W4312125541 hasPublicationYear "2022" @default.
- W4312125541 type Work @default.
- W4312125541 citedByCount "2" @default.
- W4312125541 countsByYear W43121255412023 @default.
- W4312125541 crossrefType "journal-article" @default.
- W4312125541 hasAuthorship W4312125541A5004577981 @default.
- W4312125541 hasAuthorship W4312125541A5006199350 @default.
- W4312125541 hasAuthorship W4312125541A5006737728 @default.
- W4312125541 hasAuthorship W4312125541A5008850752 @default.
- W4312125541 hasAuthorship W4312125541A5021489950 @default.