Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312137002> ?p ?o ?g. }
- W4312137002 abstract "Abstract Purpose Despite their effects on human health, the link between smokeless tobacco (ST) consumption and asthma severity in asthmatic patients is still unknown. Thus, the present study aims to complete the lack of information by investigating the aggravation of inflammation, exacerbation of asthma, oxidative stress and cytotoxicity induced by ST in asthmatic patients. Methods The study recruited 80 male volunteers residing in Annaba town, Algeria, divided into four groups by using a questionnaire, each group consists of 20 male volunteers. Herein, biochemical parameters, hematological parameters, C-reactive protein (CRP), total IgE, interleukin-5 (IL-5), nitric oxide (NO) and oxidative stress were measured. Results The obtained results showed that ST clearly enhanced lung inflammation and exacerbation of asthma through total IgE, IL-5 and CRP increased production. In addition, ST was found to intensify oxidative stress via increased lipid peroxidation and decreased reduced glutathione (GSH) levels. Likewise, the biochemical and hematological parameters results showed that ST causes damage and inflammation to tissues. Conclusion Therefore, our study reveals that ST obviously enhances allergic inflammation in patients suffering from asthma." @default.
- W4312137002 created "2023-01-04" @default.
- W4312137002 creator A5000687527 @default.
- W4312137002 creator A5027401348 @default.
- W4312137002 creator A5029385089 @default.
- W4312137002 creator A5066077498 @default.
- W4312137002 creator A5069204422 @default.
- W4312137002 creator A5091110571 @default.
- W4312137002 date "2022-12-12" @default.
- W4312137002 modified "2023-10-12" @default.
- W4312137002 title "Smokeless Tobacco Enhance Allergic Inflammation, Exacerbation of Asthma and Oxidative Stress in Asthmatic Patients from Algeria" @default.
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