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- W4312139813 abstract "<h3>Objectives</h3> This study aimed to identify clinicopathological predictive factors of axillary lymph node metastases in patients with early breast cancer. <h3>Methods</h3> We included patients with clinical T0, T1 andT2 invasive breast carcinoma who underwent resection of the primary tumor and axillary staging by sentinel lymph node biopsy and/or axillary lymph node dissection between 2012 and 2018 <h3>Results</h3> Of the 135patients included, 41.5% had ALNI. Regarding univariate analysis, clinical factors correlated with positive ALNM were clinical tumour size>30 mm(p=0.006), clinical tumour stage(p=0.047), clinical number of tumours (p=0.016),clinical axillary nodal status(p<0.001) and nodal status on ultrasound (p<0.001). Pathologic factors associated with nodal involvement were pathologic tumour stage (p=0.003), tumor grade SBR(p=0.001), number of foci (p<0.001), lympho vascular invasion(p<0.001),perineural invasion(p=0.001) and Ki67>20%(p=0.049). In multivariate logistic regression, clinical axillary nodal status (OR=4.31, CI 2.26–50, p=0.032), pathologic tumour stage (OR=3.66, CI 2–19.23, p=0.016) and lympho vascular invasion(LVI) (OR=4.29, CI 1.91–29.41, p=0.026) remained as independant predictors of ALNI. <h3>Conclusions</h3> Based on these results, we suggest that clinical axillary nodal status, pathologic tumor stage, and LVI are predictive factors for ALNM in Tunisian women with early breast cancer." @default.
- W4312139813 created "2023-01-04" @default.
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- W4312139813 date "2022-12-01" @default.
- W4312139813 modified "2023-10-18" @default.
- W4312139813 title "EP038/#548 Predictive factors of axillary lymph node involvement in Tunisian women with early breast cancer" @default.
- W4312139813 doi "https://doi.org/10.1136/ijgc-2022-igcs.129" @default.
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