FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312196415> ?p ?o ?g. }

• W4312196415 abstract "Peritoneal adhesion is a significant problem following gastrointestinal surgeries, accompanied by a significant economic burden and morbidity for patients. Punica granatum seed oil (PSO) possesses antioxidative, anti-inflammatory, and anticancer effects. Thus, we aimed to evaluate the antiperitoneal adhesive properties of PSO in rats. Forty-eight Wistar rats (200-250 g) were randomly and equally divided into six groups: sham group, control group; peritoneal adhesion without any treatment, vehicle group; peritoneal adhesion with saline + Tween-80.5% treatment, and experimental groups; peritoneal adhesion with 0.5%, 1.5%, and 4.5% v/v PSO treatment. In addition, peritoneal adhesion was examined macroscopically along with evaluating the oxidative stress (malondialdehyde [MDA], nitric oxide [NO], and glutathione [GSH]) inflammatory (interleukin [IL]-6, IL-1β, and tumor necrosis factor-α [TNF-α]), fibrotic (transforming growth factor-β [TGF-β]), and angiogenic (vascular endothelial growth factor [VEGF]) factors. Our results revealed that the levels of adhesion scores, MDA, NO, IL-6, TNF-α, IL-1β, TGF-β, and VEGF, were propagated in the vehicle group while the GSH level was alleviated (p < 0.001). In contrast, premedication with PSO, especially at the lowest concentration, notably lessened the levels of adhesion scores, MDA, NO, IL-6, TNF-α, IL-1β, TGF-β, and VEGF as well as GSH in comparison to the vehicle group following the peritoneal adhesion induction (p < 0.001-0.05). As a result, PSO may prevent peritoneal adhesion through its antioxidant, anti-inflammatory, antifibrotic, and antiangiogenic properties. Therefore, PSO could be considered a beneficial candidate for the treatment of postoperative peritoneal adhesion." @default.
• W4312196415 created "2023-01-04" @default.
• W4312196415 creator A5012139870 @default.
• W4312196415 creator A5017311650 @default.
• W4312196415 creator A5026279149 @default.
• W4312196415 creator A5041437083 @default.
• W4312196415 creator A5053233937 @default.
• W4312196415 date "2022-12-01" @default.
• W4312196415 modified "2023-10-14" @default.
• W4312196415 title "<i>Punica granatum</i> seed oil detracts peritoneal adhesion: Perusing antioxidant, anti‐inflammatory, antifibrotic, and antiangiogenic impacts" @default.
• W4312196415 cites W1611331702 @default.
• W4312196415 cites W1914843480 @default.
• W4312196415 cites W1993883849 @default.
• W4312196415 cites W2000534365 @default.
• W4312196415 cites W2007448502 @default.
• W4312196415 cites W2009597050 @default.
• W4312196415 cites W2031220614 @default.
• W4312196415 cites W2038544675 @default.
• W4312196415 cites W2043976255 @default.
• W4312196415 cites W2047023779 @default.
• W4312196415 cites W2051231896 @default.
• W4312196415 cites W2063591253 @default.
• W4312196415 cites W2069215828 @default.
• W4312196415 cites W2110582342 @default.
• W4312196415 cites W2117116552 @default.
• W4312196415 cites W2119944195 @default.
• W4312196415 cites W2128635872 @default.
• W4312196415 cites W2129324235 @default.
• W4312196415 cites W2143313489 @default.
• W4312196415 cites W2148813561 @default.
• W4312196415 cites W2149116298 @default.
• W4312196415 cites W2174659531 @default.
• W4312196415 cites W2178209387 @default.
• W4312196415 cites W2333562132 @default.
• W4312196415 cites W2517503705 @default.
• W4312196415 cites W2621938032 @default.
• W4312196415 cites W2752266230 @default.
• W4312196415 cites W2758006554 @default.
• W4312196415 cites W2769204645 @default.
• W4312196415 cites W2789466712 @default.
• W4312196415 cites W2789744985 @default.
• W4312196415 cites W2896543562 @default.
• W4312196415 cites W2903024202 @default.
• W4312196415 cites W2932457812 @default.
• W4312196415 cites W2999013265 @default.
• W4312196415 cites W3007650473 @default.
• W4312196415 cites W3011279621 @default.
• W4312196415 cites W3081807707 @default.
• W4312196415 cites W3088192797 @default.
• W4312196415 cites W3163472963 @default.
• W4312196415 cites W3193192169 @default.
• W4312196415 cites W4200213841 @default.
• W4312196415 cites W4254550628 @default.
• W4312196415 cites W4281876283 @default.
• W4312196415 cites W4293247451 @default.
• W4312196415 cites W4312196415 @default.
• W4312196415 doi "https://doi.org/10.14814/phy2.15545" @default.
• W4312196415 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36541264" @default.
• W4312196415 hasPublicationYear "2022" @default.
• W4312196415 type Work @default.
• W4312196415 citedByCount "1" @default.
• W4312196415 countsByYear W43121964152022 @default.
• W4312196415 crossrefType "journal-article" @default.
• W4312196415 hasAuthorship W4312196415A5012139870 @default.
• W4312196415 hasAuthorship W4312196415A5017311650 @default.
• W4312196415 hasAuthorship W4312196415A5026279149 @default.
• W4312196415 hasAuthorship W4312196415A5041437083 @default.
• W4312196415 hasAuthorship W4312196415A5053233937 @default.
• W4312196415 hasBestOaLocation W43121964153 @default.
• W4312196415 hasConcept C126322002 @default.
• W4312196415 hasConcept C167734588 @default.
• W4312196415 hasConcept C178790620 @default.
• W4312196415 hasConcept C17991360 @default.
• W4312196415 hasConcept C181199279 @default.
• W4312196415 hasConcept C185592680 @default.
• W4312196415 hasConcept C2776151105 @default.
• W4312196415 hasConcept C2777025900 @default.
• W4312196415 hasConcept C2778004101 @default.
• W4312196415 hasConcept C2778401633 @default.
• W4312196415 hasConcept C519581460 @default.
• W4312196415 hasConcept C538909803 @default.
• W4312196415 hasConcept C55493867 @default.
• W4312196415 hasConcept C71924100 @default.
• W4312196415 hasConcept C84416704 @default.
• W4312196415 hasConcept C98274493 @default.
• W4312196415 hasConceptScore W4312196415C126322002 @default.
• W4312196415 hasConceptScore W4312196415C167734588 @default.
• W4312196415 hasConceptScore W4312196415C178790620 @default.
• W4312196415 hasConceptScore W4312196415C17991360 @default.
• W4312196415 hasConceptScore W4312196415C181199279 @default.
• W4312196415 hasConceptScore W4312196415C185592680 @default.
• W4312196415 hasConceptScore W4312196415C2776151105 @default.
• W4312196415 hasConceptScore W4312196415C2777025900 @default.
• W4312196415 hasConceptScore W4312196415C2778004101 @default.
• W4312196415 hasConceptScore W4312196415C2778401633 @default.
• W4312196415 hasConceptScore W4312196415C519581460 @default.
• W4312196415 hasConceptScore W4312196415C538909803 @default.
• W4312196415 hasConceptScore W4312196415C55493867 @default.
• W4312196415 hasConceptScore W4312196415C71924100 @default.
• W4312196415 hasConceptScore W4312196415C84416704 @default.

• next