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• W4312210899 abstract "Abstract Objective To compare the independent and combined use of indirect computed tomographic lymphography (ICTL) and near‐infrared fluorescence (NIRF) for sentinel lymph node (SLN) mapping in dogs with integumentary mast cell tumors (MCT) and report the metastatic LN rate. Study design Prospective clinical study. Animals Twenty client‐owned dogs. Methods Dogs underwent preoperative ICTL, then intraoperative NIRF SLN mapping and excision of the anatomic lymph node (ALN) and/or SLN, and primary MCT. Technique agreement was complete if the same SLN was detected, and partial if the same SLN was detected along with additional SLN. No agreement occurred if the techniques detected different or no SLN. MCT were graded using two‐ and three‐tier schemes, and LN were graded from HN0‐3; HN2‐3 were considered metastatic. Results Complete, partial, and no agreement between ICTL and NIRF was seen in 8/20 (40%), 8/20 (40%), and 4/20 (20%) dogs, respectively. Detection of ICTL‐SLN and NIRF‐SLN failed in 1/20 (5%) and 4/20 (20%), respectively. Tumors were grade II/low‐grade in 19/20 (95%) and grade III/high‐grade in 1/20 (5%) dogs. Nineteen out of 20 (95%) dogs had HN2‐3 LN. Conclusions Technique agreement of at least one SLN was seen in 16/20 (80%) dogs. Although most MCT were classified as intermediate to low grade, LN metastases were commonly detected. Clinical significance Combining ICTL and NIRF for MCT SLN mapping yields high SLN detection rates. Lymph node metastasis may be more common than previously reported for intermediate to low grade MCT." @default.
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• W4312210899 date "2022-12-27" @default.
• W4312210899 modified "2023-09-27" @default.
• W4312210899 title "Comparison of indirect computed tomographic lymphography and near‐infrared fluorescence sentinel lymph node mapping for integumentary canine mast cell tumors" @default.
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• W4312210899 doi "https://doi.org/10.1111/vsu.13929" @default.
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