FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312218178> ?p ?o ?g. }

• W4312218178 abstract "The establishment of the gut microbiota can be influenced by several perinatal factors, including, most importantly, the maternal microbiota. Moreover, early-life environmental variation affects gut microbial colonization and the intestinal health of offspring throughout life. The present study aimed to explore the development of piglet gut microbiota from birth to weaning in the commercial practice and also to assess how different farm environments could condition this process. Although it is possible to find in the literature other studies with similar objectives this work probably represents one of the few studies that make a systematic evaluation of such differential factors under a real scenario. To achieve this objective, we performed two trials. In a first Trial, we selected 2 farms in which we performed an intensive sampling (5 samples /animal) to characterize the gut colonization pattern during the first days of life and to identify the time window with the greatest impact. Both farms differed in their health status and the use of antimicrobials in the piglets. In a second Trial, we selected 4 additional farms with variable rearing conditions and a distinctive use of antimicrobials in the sows with a simplified sampling pattern (2 samples/animal). Faecal samples were obtained with swabs and DNA was extracted by using the PSP® Spin Stool DNA Kit and sequencing of the 16S rRNA gene (V3-V4 region) performed by Illumina MiSeq Platform.The present study contributes to a better understanding of microbiome development during the transition from birth to weaning in commercial conditions. Alpha diversity was strongly affected by age, with an increased richness of species through time. Beta diversity decreased after weaning, suggesting a convergent evolvement among individuals. We pinpointed the early intestinal colonizers belonging to Bacteroides, Escherichia-Shigella, Clostridium sensu stricto 1, and Fusobacterium genera. During lactation(d7-d21 of life), the higher relative abundances of Bacteroides and Lactobacillus genera were correlated with a milk-oriented microbiome. As the piglets aged and after weaning (d36 of life), increasing abundances of genera such as Prevotella, Butyricimonas, Christensenellaceae R-7 group, Dorea, Phascolarctobacterium, Rikenellaceae RC9 gut group, Subdoligranulum, and Ruminococcaceae UCG-002 were observed. These changes indicate the adaptation of the piglets to a cereal-based diet rich in oligosaccharides and starch. Our results also show that the farm can have a significant impact in such a process, evidencing the influence of different environments and rearing systems on the gut microbiota development of the young piglet. Differences between farms were more noticeable after weaning than during lactation with changes in alpha and beta biodiversity and specific taxa. The analysis of such differences suggests that piglets receiving intramuscular amoxicillin (days 2-5 of life) and being offered an acidifying rehydrating solution (Alpha farm in Trial 1) have a greater alpha diversity and more abundant Lactobacillus population. Moreover, the only farm that did not offer any rehydrating solution (Foxtrot farm in Trial 2) showed a lower alpha diversity (day 2 of life) and increased abundance of Enterobacteriaceae (both at 2 and 21 days). The use of in-feed antibiotics in the sows was also associated with structural changes in the piglets' gut ecosystem although without changes in richness or diversity. Significant shifts could be registered in different microbial groups, particularly lower abundances of Fusobacterium in those piglets from medicated sows.In conclusion, during the first weeks of life, the pig microbiota showed a relevant succession of microbial groups towards a more homogeneous and stable ecosystem better adapted to the solid dry feed. In this relevant early-age process, the rearing conditions, the farm environment, and particularly the antimicrobial use in piglets and mothers determine changes that could have a relevant impact on gut microbiota maturation. More research is needed to elucidate the relative impact of these farm-induced early life-long changes in the growing pig." @default.
• W4312218178 created "2023-01-04" @default.
• W4312218178 creator A5020706720 @default.
• W4312218178 creator A5036311622 @default.
• W4312218178 creator A5040663364 @default.
• W4312218178 creator A5056422827 @default.
• W4312218178 creator A5068123644 @default.
• W4312218178 creator A5069430534 @default.
• W4312218178 date "2022-12-26" @default.
• W4312218178 modified "2023-10-16" @default.
• W4312218178 title "An insight into the commercial piglet’s microbial gut colonization: from birth towards weaning" @default.
• W4312218178 cites W1513022196 @default.
• W4312218178 cites W1831022746 @default.
• W4312218178 cites W1895283065 @default.
• W4312218178 cites W1926318014 @default.
• W4312218178 cites W1955747075 @default.
• W4312218178 cites W1965078483 @default.
• W4312218178 cites W1975261137 @default.
• W4312218178 cites W1983582871 @default.
• W4312218178 cites W1995757281 @default.
• W4312218178 cites W2000311971 @default.
• W4312218178 cites W2011223551 @default.
• W4312218178 cites W2011266482 @default.
• W4312218178 cites W2026006003 @default.
• W4312218178 cites W2027467762 @default.
• W4312218178 cites W2034285706 @default.
• W4312218178 cites W2037592488 @default.
• W4312218178 cites W2044451707 @default.
• W4312218178 cites W2044588930 @default.
• W4312218178 cites W2056279562 @default.
• W4312218178 cites W2057705279 @default.
• W4312218178 cites W2062805528 @default.
• W4312218178 cites W2074152062 @default.
• W4312218178 cites W2076594949 @default.
• W4312218178 cites W2093229186 @default.
• W4312218178 cites W2104142566 @default.
• W4312218178 cites W2105296185 @default.
• W4312218178 cites W2110065044 @default.
• W4312218178 cites W2117464052 @default.
• W4312218178 cites W2120668531 @default.
• W4312218178 cites W2120718555 @default.
• W4312218178 cites W2121685929 @default.
• W4312218178 cites W2133167298 @default.
• W4312218178 cites W2133428211 @default.
• W4312218178 cites W2134830426 @default.
• W4312218178 cites W2136631220 @default.
• W4312218178 cites W2155367962 @default.
• W4312218178 cites W2155884253 @default.
• W4312218178 cites W2160761420 @default.
• W4312218178 cites W2165561182 @default.
• W4312218178 cites W2167530765 @default.
• W4312218178 cites W2168634626 @default.
• W4312218178 cites W2171286410 @default.
• W4312218178 cites W2393202809 @default.
• W4312218178 cites W2401404581 @default.
• W4312218178 cites W2412421418 @default.
• W4312218178 cites W2548516377 @default.
• W4312218178 cites W2569773245 @default.
• W4312218178 cites W2611223559 @default.
• W4312218178 cites W2617951938 @default.
• W4312218178 cites W2733693493 @default.
• W4312218178 cites W2747668870 @default.
• W4312218178 cites W2773251382 @default.
• W4312218178 cites W2803846504 @default.
• W4312218178 cites W2806362852 @default.
• W4312218178 cites W2809516554 @default.
• W4312218178 cites W2870582183 @default.
• W4312218178 cites W2885034377 @default.
• W4312218178 cites W2886725973 @default.
• W4312218178 cites W2898517770 @default.
• W4312218178 cites W2906028510 @default.
• W4312218178 cites W2906742147 @default.
• W4312218178 cites W2912556764 @default.
• W4312218178 cites W2916517113 @default.
• W4312218178 cites W2918343024 @default.
• W4312218178 cites W2926238016 @default.
• W4312218178 cites W2947111272 @default.
• W4312218178 cites W2956249400 @default.
• W4312218178 cites W2966499532 @default.
• W4312218178 cites W2998866436 @default.
• W4312218178 cites W3028734945 @default.
• W4312218178 cites W3040470831 @default.
• W4312218178 cites W3041263165 @default.
• W4312218178 cites W3089459952 @default.
• W4312218178 cites W3128538475 @default.
• W4312218178 cites W3139525582 @default.
• W4312218178 cites W3154631325 @default.
• W4312218178 cites W3159288848 @default.
• W4312218178 cites W3184262129 @default.
• W4312218178 cites W3195999646 @default.
• W4312218178 cites W3206324599 @default.
• W4312218178 cites W4200280051 @default.
• W4312218178 doi "https://doi.org/10.1186/s42523-022-00221-9" @default.
• W4312218178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36572944" @default.
• W4312218178 hasPublicationYear "2022" @default.
• W4312218178 type Work @default.
• W4312218178 citedByCount "4" @default.
• W4312218178 countsByYear W43122181782023 @default.
• W4312218178 crossrefType "journal-article" @default.
• W4312218178 hasAuthorship W4312218178A5020706720 @default.

• next