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- W4312288529 abstract "<b>Rationale:</b> Identifying treatable threats in progressive fibrosing interstitial lung disease (PF-ILD) might have clinical implications. The aim of our study was to evaluate BAL microbiological profiles in progressive forms of ILDs including CTD-ILD connective tissue disorder (CTD-ILD), interstitial pneumonia with autoimmune features (IPAF) and idiopathic pulmonary fibrosis (IPF). <b>Methods:</b> In our study all CTD-ILD, IPAF and IPF patients diagnosed between 2015 and 2021 at the Department of Pulmonology, Semmelweis University who had bronchoalveolar lavage (BAL) at baseline were included (N=60). ILD diagnosis was always set by the multidisciplinary team. Pulmonary symptoms, lung function and BAL microbiology were analyzed. <b>Results:</b> Patients were divided into two groups according to the identified pathogens: Group 1 includes patients with pathogens identified though microbiological examinations (N=32, 50% males, mean age 64,3±14,6) while in Group 2 no pathogens were identified (N=28, 39,3% males, mean age 64,3±10,5 years). The most common pathogens were Staphylococcus aureus, Candida spp and Aspergillus. Multiple pathogens were identified in 21,7 % of Group 1 patients. Patients had a restrictive ventilator pattern regarding all cases (FVC%: 73,8±20,7 DLCO%: 67,2±20,7). <b>Conclusion:</b> Patients with PF-ILD with confirmed pathogens in the BAL at initial diagnosis have similar functional state to patients without any pathogens, the former represents a treatable threat and therefore treatment can have impact on long term outcome. Prospective analysis of this effect is ongoing." @default.
- W4312288529 created "2023-01-04" @default.
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- W4312288529 date "2022-09-04" @default.
- W4312288529 modified "2023-10-01" @default.
- W4312288529 title "Microbiology profile of BAL in interstitial lung disease patients" @default.
- W4312288529 doi "https://doi.org/10.1183/13993003.congress-2022.3879" @default.
- W4312288529 hasPublicationYear "2022" @default.
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