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- W4312367080 abstract "<b>Background:</b> Research on pulmonary hypertension (PH) has largely been driven by pharmaceutical companies and individual researchers. The priorities for PH research according to patients, caregivers, and clinicians have not established. <b>Aim:</b> To determine the top 10 priority questions for future research on PH according to patients and other key stakeholders. <b>Methods:</b> We conducted a Priority Setting Partnerships (PSP) for PH in Canada using the James Lind Alliance (https://www.jla.nihr.ac.uk/) methodology. A survey was distributed through Canadian patient advocacy organizations to elicit their potential questions about PH causes, diagnosis and management. These questions were verified as uncertainties after a systematic literature search. An interim prioritization survey narrowed the list of uncertainties to the top 25, which were discussed in virtual workshops in February 2022 to determine the top 10 research priorities. <b>Results:</b> There were 219 respondents (86% patients and caregivers, 14% clinicians) to the initial survey with 1588 in-scope proposed questions. From these, 187 summary questions were formulated. Most (n=157) were verified as uncertain. The consensus Top 10 list of uncertainties for future PH research from the virtual workshops are in the <b>Figure</b>. . <b>Conclusions:</b> We identified the top 10 researchable questions for future PH research, which may inform PH researchers and funding agencies where to focus resources." @default.
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- W4312367080 date "2022-09-04" @default.
- W4312367080 modified "2023-10-08" @default.
- W4312367080 title "Research priorities for future pulmonary hypertension research: a James Lind Alliance priority setting partnership" @default.
- W4312367080 doi "https://doi.org/10.1183/13993003.congress-2022.2581" @default.
- W4312367080 hasPublicationYear "2022" @default.
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