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- W4312379236 abstract "<b>Introduction:</b> Population-based studies that compare children presenting with night cough alone to those who wheeze or report both symptoms are few and inconclusive. <b>Methods:</b> We analysed data from Luftibus in the school, a population-based study of schoolchildren in Zurich, Switzerland conducted in 2013-2016. We divided children into four mutually exclusive groups based on reported night cough and wheeze, and compared reported characteristics, spirometry, FeNO, healthcare use and management. <b>Results:</b> We included 3427 children, among whom 8% reported night cough alone, 5% reported wheeze alone, 3% reported both night cough and wheeze and 83% none (asymptomatic). Children with night cough alone differed in many aspects from children with wheeze. Night cough was more strongly associated with upper respiratory symptoms while wheeze was more closely associated with a family or personal history of atopy. Lung function was reduced and FeNO increased in children with wheeze, while there was no difference between children with night cough alone and asymptomatic children. Children with night cough alone used healthcare services less often than children with wheeze, and they attended mainly primary care. Of those reporting night cough alone, however, 8% (22) reported a doctor diagnosis of asthma and asthma treatment. This subgroup shared characteristics with children with wheeze. <b>Conclusion:</b> Most children who report night cough alone do not have features typical for asthma and may not benefit from asthma diagnosis workup and treatment. Only a small subgroup (8%) has asthma-like features and might warrant further investigations. <b>Funding:</b> SNSF: 320030_182628; Lunge Zürich" @default.
- W4312379236 created "2023-01-04" @default.
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- W4312379236 date "2022-09-04" @default.
- W4312379236 modified "2023-09-28" @default.
- W4312379236 title "Night cough in children: phenotypic characterisation, healthcare utilisation, and management in a population-based study" @default.
- W4312379236 doi "https://doi.org/10.1183/13993003.congress-2022.1119" @default.
- W4312379236 hasPublicationYear "2022" @default.
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