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- W4312447652 abstract "<b>Background:</b> Several studies reported a link between sarcoidosis and an increased risk of pulmonary embolism (PE) <sup>1,2</sup>. This study aimed at assessing possible risk factors of PE in sarcoidosis patients. <b>Methods:</b> We enrolled 270 sarcoidosis patients (98 males and 172 females; mean age at diagnosis 50 ± 11). Clinical evaluations, laboratory tests and radiology features were performed, after obtained patients informed consent. <b>Results:</b> Twenty sarcoidosis patients with PE (12 females and 8 males; mean age at diagnosis 51 ± 10), diagnosed by lung scintigraphy and 250 sarcoidosis patients without PE (163 females and 87 males; mean age at diagnosis 48 ± 11), were reported. We observed a statistically significant increase of the presence of antiphospholipid antibodies in the sarcoidosis patients with PE (50%) than in sarcoidosis patients without PE (8%), p-value= 0.026. No statistically significant differences were observed between the two groups regarding smoking habit, obesity, hereditary thrombophilia frequency and treatmen regimen, at time of enrollment, p-value > 0.05, respectively. <b>Conclusions:</b> This study show that the positivity of antiphospholipid antibodies is increased in the PE sarcoidosis patients. In conclusion we advice the screening for these antibodies in all sarcoidosis patients. <b>References:</b> <b>1.</b> Singha, A., et al. Summary for Clinicians: Clinical Practice Guideline for the Diagnosis and Detection of Sarcoidosis. Annals of The American Thoracic Society. 2020, 17(12), 1510–1515. <b>2.</b> Crawshaw, A. P., et al. Evidence for association between sarcoidosis and Pulmonary embolism from 35-year record linkage study. Thorax. 2011. 66(5), 447–448." @default.
- W4312447652 created "2023-01-04" @default.
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- W4312447652 date "2022-09-04" @default.
- W4312447652 modified "2023-09-28" @default.
- W4312447652 title "Risk factor of pulmonary embolism in sarcoidosis patients: a pilot study" @default.
- W4312447652 doi "https://doi.org/10.1183/13993003.congress-2022.315" @default.
- W4312447652 hasPublicationYear "2022" @default.
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