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- W4312508743 abstract "Biopolymers are preferred materials for medical applications on account of the great biocompatibility they exhibit. Their natural origin makes them highly bioactive and eco-friendly. But poor technological properties and quick deterioration rate pose enormous challenges on their performance and utility in proposed applications. The issues associated with lack of desired mechanical properties and aqueous stability of biopolymers can be managed to a great extent through cross-linking. Cross-linked biopolymers are found to behold great potential for biomedical applications like tissue engineering, drug delivery, and wound healing. Although, cross linking enables the biopolymers to meet the prerequisite of mechanical strength for various applications, it negatively interferes with other natural properties that made these biopolymers highly beneficial for biomedical applications. The reduction in degradability associated with cross-linking will have a negative impact while fabricating biomaterials for implants and drug delivery systems in general. On the other hand, this negative side effect is extremely necessary and beneficial when longevity of implants or prolonged duration delivery of the pharmaceutical agent has to be ensured. Thus the equilibrium between mechanical strength and degradability must be decided during cross-linking biopolymers for their efficient functioning. Among the various options for biopolymer cross linking, the highly favored chemical cross-linking comes along with the grave disadvantage of cytotoxicity. In this regard, finding sustainable methods of cross-linking and newer cross-linkers are thrust areas of concern in order to ensure desired properties to biopolymers for medical applications. This chapter discusses about the main biopolymers, their cross-linking strategies, and the biomedical applications of cross-linked biopolymers." @default.
- W4312508743 created "2023-01-05" @default.
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- W4312508743 date "2022-01-01" @default.
- W4312508743 modified "2023-09-25" @default.
- W4312508743 title "Cross-Linking Biopolymers for Biomedical Applications" @default.
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- W4312508743 doi "https://doi.org/10.1007/978-981-16-6603-2_42-1" @default.
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