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- W4312548725 abstract "Introduction: Strongyloides stercoralis is an intestinal nematode with nonspecific gastrointestinal symptoms. In transplant patients, disseminated strongyloidiasis carries a mortality rate of 80%. Case report: The patient is a 54 year old athlete who underwent liver transplant in 2019. He is normally extremely physically active. He presented one year post-transplant with three days of diffuse gnawing abdominal pain that came in waves. He noted recent ten-pound weight gain and constant fatigue. Labs suggested malnutrition requiring parenteral nutrition. Endoscopies were negative. Rejection and tumor workups were negative. He continued to have diffuse abdominal pain, anorexia and constipation. He began to have hypotension and persistent fevers, but blood cultures were negative. He stayed in bed feeling depressed and “constantly drained”. With worsening bloating and epigastric pain, a repeat endoscopy was performed. Multiple patches of friable erythematous mucosa were noted in the stomach and duodenum. Biopsies demonstrated parasitic worms, confirmed to be Strongyloides. Treatment with Ivermectin was initiated. He had complete resolution of his symptoms within four days, including a dramatic improvement in mood and motivation. It was discovered that a week before the onset of his symptoms, the patient had adopted a dog with no vaccination record, believed to have been a parasitic host. The time from exposure to hospitalization was one week. Conclusions: Disseminated strongyloidiasis is characterized by overwhelming worm burden causing sepsis, shock and gastrointestinal failure. It is important for clinicians to recognize the atypical physical and mental symptoms, as well as the rapid resolution with proper treatment in transplant patients." @default.
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- W4312548725 date "2022-01-01" @default.
- W4312548725 modified "2023-09-26" @default.
- W4312548725 title "Rapidly Disseminated Strogyloidiasis Following Liver Transplant" @default.
- W4312548725 doi "https://doi.org/10.1016/j.hpb.2022.05.1257" @default.
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