Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312551408> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W4312551408 abstract "<h3>Introduction/Background</h3> The MULTISENT study is an initiative that aims to analyze the clinical application of sentinel lumph-node(SLN) technique in Spain. This abstract presents the second objective of the study, aiming to evaluate the rate of SLN metastases detected and the impact of the volume of the disease on the survival of the patients. <h3>Methodology</h3> Multicenter retrospective study in which twenty-nine Spanish centers were enrolled. Patients operated between 2015–2021 with preoperative clinical stage I-II EC and undergoing SLN mapping as part of their surgical protocol were included. SLN mapping was performed with three different tracers(ICG, ICG + 99mTC and 99mTC alone or in combination with blue dyes) and different sites of injections were used(cervical, uterus and both). Pelvic lymphadenectomy was performed in 54% of the cohort and aortic lymphadenectomy in 26%, according to the preoperative risk of the patient and the institutional protocol. OSNA or ultra-staging protocols with immunohistochemistry were used to study SLN specimens. <h3>Results</h3> 1182 eligible patients were analyzed. Median age was 62.7 y(55.9–70.5 y). Median number of resected SLNs was 2(range 1–3) per patient. Minimally-invasive surgeries were performed in 1127(95%) patients. 117 patients(9.9%) had positive SLNs, 68 patients(5.7%) with macrometastases and 49(4.2%) with low-volume disease(24 micrometastases and 25 isolated tumour cells, ITC). Patients with macrometastases had a significantly higher proportion of non-endometrioid histologies, grade 3, lymph-vascular invasion, and received more extensive surgery and adjuvant chemotherapy. False-negative rate(FNR) of the SLN technique in the cohort was 1.6%. With a median follow up of 1.8 y(0.9–3 y), patients with macrometastases in SLN showed a decreased overall survival(OS) and disease-free survival(DFS) when compared to patients with negative SLN, ITC or micrometastases (figure1). <h3>Conclusion</h3> SLN is a feasible technique with high sensitivity and low false-negative rate. Patients with macrometastasis showed the worst results in terms of OS and DFS." @default.
- W4312551408 created "2023-01-05" @default.
- W4312551408 creator A5006579817 @default.
- W4312551408 creator A5013389573 @default.
- W4312551408 creator A5020798494 @default.
- W4312551408 creator A5024245549 @default.
- W4312551408 creator A5025679004 @default.
- W4312551408 creator A5033045148 @default.
- W4312551408 creator A5033087327 @default.
- W4312551408 creator A5037049238 @default.
- W4312551408 creator A5038569178 @default.
- W4312551408 creator A5039389940 @default.
- W4312551408 creator A5050043493 @default.
- W4312551408 creator A5052767637 @default.
- W4312551408 creator A5065976273 @default.
- W4312551408 creator A5070924456 @default.
- W4312551408 creator A5073016946 @default.
- W4312551408 creator A5080269930 @default.
- W4312551408 creator A5088350515 @default.
- W4312551408 creator A5091745152 @default.
- W4312551408 date "2022-10-01" @default.
- W4312551408 modified "2023-10-18" @default.
- W4312551408 title "2022-RA-1509-ESGO The MULTISENT study: Analysis of survival according to the volume of sentinel lymph node disease" @default.
- W4312551408 doi "https://doi.org/10.1136/ijgc-2022-esgo.333" @default.
- W4312551408 hasPublicationYear "2022" @default.
- W4312551408 type Work @default.
- W4312551408 citedByCount "0" @default.
- W4312551408 crossrefType "proceedings-article" @default.
- W4312551408 hasAuthorship W4312551408A5006579817 @default.
- W4312551408 hasAuthorship W4312551408A5013389573 @default.
- W4312551408 hasAuthorship W4312551408A5020798494 @default.
- W4312551408 hasAuthorship W4312551408A5024245549 @default.
- W4312551408 hasAuthorship W4312551408A5025679004 @default.
- W4312551408 hasAuthorship W4312551408A5033045148 @default.
- W4312551408 hasAuthorship W4312551408A5033087327 @default.
- W4312551408 hasAuthorship W4312551408A5037049238 @default.
- W4312551408 hasAuthorship W4312551408A5038569178 @default.
- W4312551408 hasAuthorship W4312551408A5039389940 @default.
- W4312551408 hasAuthorship W4312551408A5050043493 @default.
- W4312551408 hasAuthorship W4312551408A5052767637 @default.
- W4312551408 hasAuthorship W4312551408A5065976273 @default.
- W4312551408 hasAuthorship W4312551408A5070924456 @default.
- W4312551408 hasAuthorship W4312551408A5073016946 @default.
- W4312551408 hasAuthorship W4312551408A5080269930 @default.
- W4312551408 hasAuthorship W4312551408A5088350515 @default.
- W4312551408 hasAuthorship W4312551408A5091745152 @default.
- W4312551408 hasBestOaLocation W43125514081 @default.
- W4312551408 hasConcept C121608353 @default.
- W4312551408 hasConcept C126322002 @default.
- W4312551408 hasConcept C126838900 @default.
- W4312551408 hasConcept C141071460 @default.
- W4312551408 hasConcept C142724271 @default.
- W4312551408 hasConcept C146357865 @default.
- W4312551408 hasConcept C151730666 @default.
- W4312551408 hasConcept C167135981 @default.
- W4312551408 hasConcept C2779720271 @default.
- W4312551408 hasConcept C2780212769 @default.
- W4312551408 hasConcept C2780824555 @default.
- W4312551408 hasConcept C2780849966 @default.
- W4312551408 hasConcept C530470458 @default.
- W4312551408 hasConcept C71924100 @default.
- W4312551408 hasConcept C86803240 @default.
- W4312551408 hasConceptScore W4312551408C121608353 @default.
- W4312551408 hasConceptScore W4312551408C126322002 @default.
- W4312551408 hasConceptScore W4312551408C126838900 @default.
- W4312551408 hasConceptScore W4312551408C141071460 @default.
- W4312551408 hasConceptScore W4312551408C142724271 @default.
- W4312551408 hasConceptScore W4312551408C146357865 @default.
- W4312551408 hasConceptScore W4312551408C151730666 @default.
- W4312551408 hasConceptScore W4312551408C167135981 @default.
- W4312551408 hasConceptScore W4312551408C2779720271 @default.
- W4312551408 hasConceptScore W4312551408C2780212769 @default.
- W4312551408 hasConceptScore W4312551408C2780824555 @default.
- W4312551408 hasConceptScore W4312551408C2780849966 @default.
- W4312551408 hasConceptScore W4312551408C530470458 @default.
- W4312551408 hasConceptScore W4312551408C71924100 @default.
- W4312551408 hasConceptScore W4312551408C86803240 @default.
- W4312551408 hasLocation W43125514081 @default.
- W4312551408 hasOpenAccess W4312551408 @default.
- W4312551408 hasPrimaryLocation W43125514081 @default.
- W4312551408 hasRelatedWork W1973718469 @default.
- W4312551408 hasRelatedWork W1995700936 @default.
- W4312551408 hasRelatedWork W2002742161 @default.
- W4312551408 hasRelatedWork W2082683773 @default.
- W4312551408 hasRelatedWork W2093959080 @default.
- W4312551408 hasRelatedWork W2168821180 @default.
- W4312551408 hasRelatedWork W2387549903 @default.
- W4312551408 hasRelatedWork W4319299746 @default.
- W4312551408 hasRelatedWork W1739700908 @default.
- W4312551408 hasRelatedWork W2497164625 @default.
- W4312551408 isParatext "false" @default.
- W4312551408 isRetracted "false" @default.
- W4312551408 workType "article" @default.