Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312621084> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W4312621084 abstract "Ethionine (CAS # 13073-35-3) is an S-ethyl analog of methionine. It is an antimetabolite that interferes with the synthesis of S-adenosylmethionine, a principal methyl donor of proteins, nucleic acids, and cellular structures. The major toxicity of ethionine includes liver steatosis and hepatocarcinoma. Methionine is an effective antidote for reversing ethionine toxicity. It can produce liver neoplasms. It is produced by various microorganisms such as E. coli and used as an experimental carcinogen in biological research. When a small number of patients with advanced neoplasias were placed on a diet deficient in methionine and exposed to ethionine orally (0.67–45 g/day; total doses 9.7–55 g), it produced a range of symptoms: (i) impairment of liver function, (ii) proteinuria, (iii) hematuria, (iv) dermatitis, (v) leukopenia, (vi) thrombocytopenia and (vii) diarrhea. Deterioration of mental status & frank toxic psychosis were also observed." @default.
- W4312621084 created "2023-01-05" @default.
- W4312621084 creator A5033759807 @default.
- W4312621084 creator A5078338119 @default.
- W4312621084 date "2023-01-01" @default.
- W4312621084 modified "2023-09-29" @default.
- W4312621084 title "Ethionine" @default.
- W4312621084 cites W1199090597 @default.
- W4312621084 cites W1998862010 @default.
- W4312621084 cites W2024729749 @default.
- W4312621084 cites W2057210916 @default.
- W4312621084 cites W2093415711 @default.
- W4312621084 cites W2098205801 @default.
- W4312621084 cites W2151439672 @default.
- W4312621084 cites W2274120444 @default.
- W4312621084 cites W2580537874 @default.
- W4312621084 cites W2994768844 @default.
- W4312621084 cites W3093608784 @default.
- W4312621084 cites W4234613859 @default.
- W4312621084 doi "https://doi.org/10.1016/b978-0-12-824315-2.00340-7" @default.
- W4312621084 hasPublicationYear "2023" @default.
- W4312621084 type Work @default.
- W4312621084 citedByCount "0" @default.
- W4312621084 crossrefType "book-chapter" @default.
- W4312621084 hasAuthorship W4312621084A5033759807 @default.
- W4312621084 hasAuthorship W4312621084A5078338119 @default.
- W4312621084 hasConcept C126322002 @default.
- W4312621084 hasConcept C185592680 @default.
- W4312621084 hasConcept C2779365888 @default.
- W4312621084 hasConcept C2780486903 @default.
- W4312621084 hasConcept C2780873365 @default.
- W4312621084 hasConcept C2780912031 @default.
- W4312621084 hasConcept C29730261 @default.
- W4312621084 hasConcept C515207424 @default.
- W4312621084 hasConcept C55493867 @default.
- W4312621084 hasConcept C71924100 @default.
- W4312621084 hasConcept C98274493 @default.
- W4312621084 hasConceptScore W4312621084C126322002 @default.
- W4312621084 hasConceptScore W4312621084C185592680 @default.
- W4312621084 hasConceptScore W4312621084C2779365888 @default.
- W4312621084 hasConceptScore W4312621084C2780486903 @default.
- W4312621084 hasConceptScore W4312621084C2780873365 @default.
- W4312621084 hasConceptScore W4312621084C2780912031 @default.
- W4312621084 hasConceptScore W4312621084C29730261 @default.
- W4312621084 hasConceptScore W4312621084C515207424 @default.
- W4312621084 hasConceptScore W4312621084C55493867 @default.
- W4312621084 hasConceptScore W4312621084C71924100 @default.
- W4312621084 hasConceptScore W4312621084C98274493 @default.
- W4312621084 hasLocation W43126210841 @default.
- W4312621084 hasOpenAccess W4312621084 @default.
- W4312621084 hasPrimaryLocation W43126210841 @default.
- W4312621084 hasRelatedWork W1541896029 @default.
- W4312621084 hasRelatedWork W1978062885 @default.
- W4312621084 hasRelatedWork W2056410831 @default.
- W4312621084 hasRelatedWork W2098694955 @default.
- W4312621084 hasRelatedWork W2135093951 @default.
- W4312621084 hasRelatedWork W2333334920 @default.
- W4312621084 hasRelatedWork W2411938550 @default.
- W4312621084 hasRelatedWork W2748952813 @default.
- W4312621084 hasRelatedWork W2899084033 @default.
- W4312621084 hasRelatedWork W3719474 @default.
- W4312621084 isParatext "false" @default.
- W4312621084 isRetracted "false" @default.
- W4312621084 workType "book-chapter" @default.