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• W4312639934 abstract "The World Health Organization has designated carbapenem-resistant Acinetobacter baumannii (CRAB) as a critical pathogen on the global priority list of antibiotic-resistant bacteria. This study aims to discuss the molecular epidemiology of CRAB isolates in Turkiye in the last 12 years and the prevalence of gene regions associated with resistance or pathogenesis using a systematic review method. Our study consists of a literature search, determination of eligibility and exclusion criteria, qualitative analysis of studies, data extraction, and statistical analysis. All studies were analyzed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Guidelines. The incidence rates of blaOXA-23, blaOXA-23-like, blaOXA-24/40, blaOXA-24/40-like, blaOXA-51, blaOXA-51-like, blaOXA-58, and blaOXA-58-like genes in CRAB strains were 76.4%, 68.6%, 1.2%, 3.4%, 97.0%, 98.6%, 8.4%, and 17.1%, respectively. It was determined that the prevalence of the blaOXA-23 and blaOXA-58 gene regions showed a statistically significant change over the years. Due to the high prevalence of A. baumannii strains carrying the blaOXA-23 variant, it is necessary to follow its geographical distribution and transposon and plasmid movements. Based on available data, molecular surveillance of CRAB strains should be standardized. In addition, sterilization and disinfection processes applied within the scope of an effective struggle against CRAB strains that can remain live on surfaces for a long time should be reviewed frequently." @default.
• W4312639934 created "2023-01-05" @default.
• W4312639934 creator A5031673711 @default.
• W4312639934 date "2023-01-01" @default.
• W4312639934 modified "2023-09-26" @default.
• W4312639934 title "Molecular Epidemiology of Carbapenem-Resistant Acinetobacter baumannii Isolates in Turkey: Systematic Review" @default.
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• W4312639934 doi "https://doi.org/10.14744/nci.2022.17003" @default.
• W4312639934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37719251" @default.
• W4312639934 hasPublicationYear "2023" @default.
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