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- W4312700188 abstract "The catalyzing power of enzymes is the reason for life to sustain. Food can augment or deplete the influence on the production of drug-metabolizing enzymes (DMEs). Nutrient diversity like macro- and micronutrients, feeding time, starvation, and fasting duration affect the production of liver enzymatic proteins differently. Different types of dietary proteins have the escalating potential of hepatic microsomal CYP450 enzymes and liver weight. Essential fatty acids especially phosphatidylcholine can enhance the functions of DMEs. The type of fatty acid and the quantity of fats in the diet is a great dietary factor for inducing DMEs production. The calorie restriction to a certain limit and intermittent fasting was found beneficial and had positive effects on liver detoxification and production of CYP450 enzymes. But malnutrition is strongly associated with liver dysfunction as well as drug metabolism. Intraindividual diet-induced drug metabolism is a complex process; however, the latest researches showed that a diet rich in antioxidants and amino acids can enhance the hepatic drugs metabolizing enzyme production and enhance detoxification." @default.
- W4312700188 created "2023-01-05" @default.
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- W4312700188 date "2022-01-01" @default.
- W4312700188 modified "2023-09-23" @default.
- W4312700188 title "Dietary sources of drug-metabolizing enzymes: From production to regulation" @default.
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- W4312700188 doi "https://doi.org/10.1016/b978-0-323-95120-3.00002-6" @default.
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