Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312721309> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4312721309 abstract "Reducing non-specific adsorption of proteins on the surface of magnetic nanoparticles (MNPs) is becoming increasingly important. In this paper, we proposed a novel surface modification procedure by grafting hyperbranched polyglycerol (HPG) onto the surface of MNPs (Fe3O4@SiO2@MAA), in which lots of hydroxyl groups from HPG not only provide the hydrates sheath to prevent non-specific adsorption of proteins, but also react with succinic anhydride to generate carboxyl groups that serve as active sites to specifically bind proteins. The protein adsorption experiments showed that the non-specific adsorption (0.07 μg mg-1) was reduced to 4.58% of that before modification. It also showed that the antigen binding capacity was 9.7 times higher than the original when detecting cardiac troponin I (cTnI) in human plasma samples, which indicated that the final synthesized MNPs had great application prospects in bio-separation and bioanalysis." @default.
- W4312721309 created "2023-01-05" @default.
- W4312721309 creator A5032411154 @default.
- W4312721309 creator A5074140059 @default.
- W4312721309 creator A5086906808 @default.
- W4312721309 date "2022-01-01" @default.
- W4312721309 modified "2023-09-30" @default.
- W4312721309 title "REDUCING NON-SPECIFIC ADSORPTION OF PROTEINS VIA THE HPG MODIFICATION ON THE SURFACE OF MAGNETIC NANOPARTICLES" @default.
- W4312721309 doi "https://doi.org/10.21577/0100-4042.20170950" @default.
- W4312721309 hasPublicationYear "2022" @default.
- W4312721309 type Work @default.
- W4312721309 citedByCount "0" @default.
- W4312721309 crossrefType "journal-article" @default.
- W4312721309 hasAuthorship W4312721309A5032411154 @default.
- W4312721309 hasAuthorship W4312721309A5074140059 @default.
- W4312721309 hasAuthorship W4312721309A5086906808 @default.
- W4312721309 hasBestOaLocation W43127213091 @default.
- W4312721309 hasConcept C115537861 @default.
- W4312721309 hasConcept C12554922 @default.
- W4312721309 hasConcept C127413603 @default.
- W4312721309 hasConcept C137535248 @default.
- W4312721309 hasConcept C147789679 @default.
- W4312721309 hasConcept C150394285 @default.
- W4312721309 hasConcept C155672457 @default.
- W4312721309 hasConcept C171250308 @default.
- W4312721309 hasConcept C178790620 @default.
- W4312721309 hasConcept C185592680 @default.
- W4312721309 hasConcept C188027245 @default.
- W4312721309 hasConcept C192562407 @default.
- W4312721309 hasConcept C21951064 @default.
- W4312721309 hasConcept C2777735259 @default.
- W4312721309 hasConcept C42360764 @default.
- W4312721309 hasConcept C43617362 @default.
- W4312721309 hasConcept C86803240 @default.
- W4312721309 hasConcept C87023908 @default.
- W4312721309 hasConcept C88001094 @default.
- W4312721309 hasConceptScore W4312721309C115537861 @default.
- W4312721309 hasConceptScore W4312721309C12554922 @default.
- W4312721309 hasConceptScore W4312721309C127413603 @default.
- W4312721309 hasConceptScore W4312721309C137535248 @default.
- W4312721309 hasConceptScore W4312721309C147789679 @default.
- W4312721309 hasConceptScore W4312721309C150394285 @default.
- W4312721309 hasConceptScore W4312721309C155672457 @default.
- W4312721309 hasConceptScore W4312721309C171250308 @default.
- W4312721309 hasConceptScore W4312721309C178790620 @default.
- W4312721309 hasConceptScore W4312721309C185592680 @default.
- W4312721309 hasConceptScore W4312721309C188027245 @default.
- W4312721309 hasConceptScore W4312721309C192562407 @default.
- W4312721309 hasConceptScore W4312721309C21951064 @default.
- W4312721309 hasConceptScore W4312721309C2777735259 @default.
- W4312721309 hasConceptScore W4312721309C42360764 @default.
- W4312721309 hasConceptScore W4312721309C43617362 @default.
- W4312721309 hasConceptScore W4312721309C86803240 @default.
- W4312721309 hasConceptScore W4312721309C87023908 @default.
- W4312721309 hasConceptScore W4312721309C88001094 @default.
- W4312721309 hasLocation W43127213091 @default.
- W4312721309 hasOpenAccess W4312721309 @default.
- W4312721309 hasPrimaryLocation W43127213091 @default.
- W4312721309 hasRelatedWork W2097929080 @default.
- W4312721309 hasRelatedWork W2099239340 @default.
- W4312721309 hasRelatedWork W2187090595 @default.
- W4312721309 hasRelatedWork W2748952813 @default.
- W4312721309 hasRelatedWork W3008507829 @default.
- W4312721309 hasRelatedWork W3133521312 @default.
- W4312721309 hasRelatedWork W3158302372 @default.
- W4312721309 hasRelatedWork W3159020288 @default.
- W4312721309 hasRelatedWork W4312721309 @default.
- W4312721309 hasRelatedWork W748675471 @default.
- W4312721309 isParatext "false" @default.
- W4312721309 isRetracted "false" @default.
- W4312721309 workType "article" @default.