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- W4312729720 abstract "The anxiolytic effect of a new series of C2,C3-quinoxaline derivatives was studied using the Anxious-phobic state and Light/Dark chamber techniques in comparison with diazepam. It was noted that the presence of a phenyl substituent at the C3 position, which did not contain elements with a distinct electronegativity, as well as 2-methyl-(4,5-dimethoxyphenyl)-N-methylethane-1-amine at the C2 position, had a positive effect on the manifestation of the antianxiety activity of new derivatives of C2,C3-quinoxaline. For the most active compound under the code ZDM-4, the conflict method Vogel Conflict test was additionally carried out to confirm the anxiolytic effect of the substance. The tranquiLizing potential of the ZDM-4 compound is of interest for further study." @default.
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- W4312729720 date "2022-02-15" @default.
- W4312729720 modified "2023-10-16" @default.
- W4312729720 title "ASSESSMENT OF ANXIOLYTIC POTENTIAL OF NEW С2,С3- QUINOXALINE DERIVATIVES" @default.
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- W4312729720 doi "https://doi.org/10.19163/1994-9480-2022-19-2-135-142" @default.
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