FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312778872> ?p ?o ?g. }

• W4312778872 endingPage "158" @default.
• W4312778872 startingPage "154" @default.
• W4312778872 abstract "Nanoparticles are used in many everyday products because of their innovative properties, but there are concerns that, being smaller than conventional materials, they have the potential to induce unexpected biological effects. Despite the need for the safety of nanoparticles to be assessed, action in this area is still lagging. Several studies, including those by us, have revealed that nanoparticles can reach the placenta and show placental toxicity, but it remains unclear how nanoparticles affect placental function. Here, we attempted to assess the effect of nanoparticles on placental hormone-producing function by using an in vitro forskolin-induced BeWo syncytialization model. BeWo cells were treated with amorphous silica nanoparticles with a diameter of 10 nm (nSP10) either during syncytialization or after being syncytialized by forskolin treatment. RT-PCR analysis showed that nSP10 inhibited forskolin-induced upregulation in the expression level of human chorionic gonadotropin β (hCGβ; gene name, CGB) during syncytialization, but not in syncytialized BeWo cells. Moreover, nSP10 downregulated forskolin-induced elevation in the expression of endogenous retrovirus group FRD member 1 (ERVFRD-1) and syndecan-1 (SDC1), which are involved in cell fusion during syncytialization. These results suggest that nSP10 could suppress trophoblast cell fusion, thus inhibiting the production of hCG in syncytialized BeWo cells." @default.
• W4312778872 created "2023-01-05" @default.
• W4312778872 creator A5008699926 @default.
• W4312778872 creator A5020407599 @default.
• W4312778872 creator A5022142360 @default.
• W4312778872 creator A5043132959 @default.
• W4312778872 creator A5045078904 @default.
• W4312778872 creator A5074694539 @default.
• W4312778872 creator A5077923732 @default.
• W4312778872 creator A5088219268 @default.
• W4312778872 date "2022-01-01" @default.
• W4312778872 modified "2023-10-14" @default.
• W4312778872 title "Amorphas Silica Nanoparticles Decrease Human Chorionic Gonadotropin β Expression During Syncytialization of BeWo Cell" @default.
• W4312778872 cites W1160326939 @default.
• W4312778872 cites W1536661698 @default.
• W4312778872 cites W1966318343 @default.
• W4312778872 cites W1970735174 @default.
• W4312778872 cites W1989640034 @default.
• W4312778872 cites W1990960273 @default.
• W4312778872 cites W2023918126 @default.
• W4312778872 cites W2052410554 @default.
• W4312778872 cites W2083081322 @default.
• W4312778872 cites W2084378748 @default.
• W4312778872 cites W2153104756 @default.
• W4312778872 cites W2324971800 @default.
• W4312778872 cites W2397309860 @default.
• W4312778872 cites W2886376271 @default.
• W4312778872 cites W2901715201 @default.
• W4312778872 cites W2919736910 @default.
• W4312778872 cites W2972606494 @default.
• W4312778872 cites W3008978910 @default.
• W4312778872 cites W3020986724 @default.
• W4312778872 cites W3094293373 @default.
• W4312778872 cites W3118686410 @default.
• W4312778872 cites W3157474572 @default.
• W4312778872 cites W4226343892 @default.
• W4312778872 cites W4283737565 @default.
• W4312778872 cites W4286209806 @default.
• W4312778872 cites W4288437694 @default.
• W4312778872 doi "https://doi.org/10.1248/bpbreports.5.6_154" @default.
• W4312778872 hasPublicationYear "2022" @default.
• W4312778872 type Work @default.
• W4312778872 citedByCount "0" @default.
• W4312778872 crossrefType "journal-article" @default.
• W4312778872 hasAuthorship W4312778872A5008699926 @default.
• W4312778872 hasAuthorship W4312778872A5020407599 @default.
• W4312778872 hasAuthorship W4312778872A5022142360 @default.
• W4312778872 hasAuthorship W4312778872A5043132959 @default.
• W4312778872 hasAuthorship W4312778872A5045078904 @default.
• W4312778872 hasAuthorship W4312778872A5074694539 @default.
• W4312778872 hasAuthorship W4312778872A5077923732 @default.
• W4312778872 hasAuthorship W4312778872A5088219268 @default.
• W4312778872 hasBestOaLocation W43127788721 @default.
• W4312778872 hasConcept C104317684 @default.
• W4312778872 hasConcept C126322002 @default.
• W4312778872 hasConcept C127561419 @default.
• W4312778872 hasConcept C134018914 @default.
• W4312778872 hasConcept C1491633281 @default.
• W4312778872 hasConcept C172680121 @default.
• W4312778872 hasConcept C185592680 @default.
• W4312778872 hasConcept C202751555 @default.
• W4312778872 hasConcept C2775948956 @default.
• W4312778872 hasConcept C2776953305 @default.
• W4312778872 hasConcept C2777495146 @default.
• W4312778872 hasConcept C2779234561 @default.
• W4312778872 hasConcept C2779276759 @default.
• W4312778872 hasConcept C54355233 @default.
• W4312778872 hasConcept C55493867 @default.
• W4312778872 hasConcept C71315377 @default.
• W4312778872 hasConcept C71924100 @default.
• W4312778872 hasConcept C86803240 @default.
• W4312778872 hasConcept C92488253 @default.
• W4312778872 hasConcept C95444343 @default.
• W4312778872 hasConceptScore W4312778872C104317684 @default.
• W4312778872 hasConceptScore W4312778872C126322002 @default.
• W4312778872 hasConceptScore W4312778872C127561419 @default.
• W4312778872 hasConceptScore W4312778872C134018914 @default.
• W4312778872 hasConceptScore W4312778872C1491633281 @default.
• W4312778872 hasConceptScore W4312778872C172680121 @default.
• W4312778872 hasConceptScore W4312778872C185592680 @default.
• W4312778872 hasConceptScore W4312778872C202751555 @default.
• W4312778872 hasConceptScore W4312778872C2775948956 @default.
• W4312778872 hasConceptScore W4312778872C2776953305 @default.
• W4312778872 hasConceptScore W4312778872C2777495146 @default.
• W4312778872 hasConceptScore W4312778872C2779234561 @default.
• W4312778872 hasConceptScore W4312778872C2779276759 @default.
• W4312778872 hasConceptScore W4312778872C54355233 @default.
• W4312778872 hasConceptScore W4312778872C55493867 @default.
• W4312778872 hasConceptScore W4312778872C71315377 @default.
• W4312778872 hasConceptScore W4312778872C71924100 @default.
• W4312778872 hasConceptScore W4312778872C86803240 @default.
• W4312778872 hasConceptScore W4312778872C92488253 @default.
• W4312778872 hasConceptScore W4312778872C95444343 @default.
• W4312778872 hasIssue "6" @default.
• W4312778872 hasLocation W43127788721 @default.
• W4312778872 hasOpenAccess W4312778872 @default.
• W4312778872 hasPrimaryLocation W43127788721 @default.
• W4312778872 hasRelatedWork W1975696001 @default.

• next