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- W4312782015 abstract "Chitosan is an abundant naturally sourced polymer that exhibits coveted properties of biodegradability, bioactivity, non-toxicity, and polycationic character and their significant antimicrobial, antitumor, antioxidative, anticholesterolemic, hemostatic, and analgesic ramifications. Chitosan-based nanoparticles have revolutionized antibacterial dispersions owing to their capacity to amplify the action of the parent chitosan’s inherent effect. The degree of deacetylation of parent chitosan, molecular weight as well as concentration and size of nanoparticles is the various factors affecting its activity. The proof of its versatility has been its crucial applications in per-oral administration of drugs, delivery of parenteral drugs, delivery of vaccines, delivery of non-viral genes, delivery of brain targeting drugs, delivery of mucosal drugs, delivery of ocular drugs, instability improvement in controlled drug delivery of drugs, and tissue engineering. Chitosan-based system efficacy in both organic and inorganic formulations has been favored by its polycationic character which interacts with the negatively charged residues of macromolecules at the exterior. There are numerous pieces of evidence enumerating chitosan-based nanoparticles’ antibacterial properties involving testing against detrimental microbes like Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Staphylococcus aureus. Currently accelerated development of chitosan-based nanoparticles is being carried out in the medical industry for the creation of improved wound dressings, dental and orthopedic mediums, and drug delivery carriers, in defense against plant pathogens, and in the food packaging industry which has increased its relevance in the mainstream." @default.
- W4312782015 created "2023-01-05" @default.
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- W4312782015 creator A5085714120 @default.
- W4312782015 date "2022-01-01" @default.
- W4312782015 modified "2023-09-26" @default.
- W4312782015 title "Role of Antibacterial Agents Derived from Chitosan-Based Nanocomposites" @default.
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