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- W4312832020 endingPage "1680" @default.
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- W4312832020 abstract "Occupational, accidental, diagnostic, or therapeutic exposure to ionizing radiation (IR) in today’s world is inevitable. Radiation, a known mutagen, can also impart transgenerational effects and lead to life-threatening diseases like cancer, cardiovascular, diabetes, or neurological disorders. Recently, epigenetic effects of radiation exposure are being elaborately studied worldwide. DNA methylation and histone modifications (acetylation, methylation, phosphorylation, and sumoylation)-led chromatin remodeling and subsequent alterations in gene expression pattern are being studied more explicitly in various pathophysiological or stress conditions. Epidrugs can modulate the epigenetic aberrations caused due to radiation or other stress exposure. In this chapter, alteration in epigenome due to radiation exposure and the diseases conditions associated will be discussed along with their possible modification by epidrugs to improve life conditions for postradiotherapy patients." @default.
- W4312832020 created "2023-01-05" @default.
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- W4312832020 date "2022-01-01" @default.
- W4312832020 modified "2023-09-26" @default.
- W4312832020 title "Radiation-Induced Epigenetic Changes and Their Modulation by Epidrugs" @default.
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- W4312832020 doi "https://doi.org/10.1007/978-981-16-5422-0_84" @default.
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