FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312882925> ?p ?o ?g. }

• W4312882925 endingPage "37" @default.
• W4312882925 startingPage "23" @default.
• W4312882925 abstract "Oral cancers (OCs), being one of the frequent malignancies in the head and neck region, need prompt diagnosis and treatment. Apart from basic therapeutic modalities, immunotherapy has now been utilized as a novel approach to combat the disease. With the comprehension of the strategies adopted by cancer cells to evade the immune elimination by the body's immune system, targeted immunotherapies have now become the core area of research. The immune expression of epidermal growth factor receptor (EGFR), programmed cell death protein ligand-1 (PDL-1), etc., are enhanced in OC and have been associated with evasion of the immune system. Targeted immunotherapies now include monoclonal antibodies targeting EGFR like cetuximab and panitumumab, programmed cell death-1 (PD-1) inhibitors like pembrolizumab, cemiplimab, and nivolumab, and PD-L1 inhibitors like atezolizumab, avelumab, and durvalumab. Targeted immunotherapies like chimeric antigen receptor T-cell treatment and small molecule inhibitors are in several clinical trials tried as monotherapy and adjuvant immunotherapy and have shown promising results. Other immunothera-peutic approaches such as cytokines like interferons or interleukins, vaccines, and gene therapy have also been an area of research for the management of OC. However, the cautious selection of appropriate patients with specific immune characteristics as a candidate for immunotherapeutic agents is a crucial component of targeted immunotherapy. This article elaborates on the immune contexture of oral cancer cells, the mechanism of immune evasion by cancer cells, targets for immunotherapies, existent immunotherapeutic agents, and prospects in the field of immunotherapy." @default.
• W4312882925 created "2023-01-05" @default.
• W4312882925 creator A5033595890 @default.
• W4312882925 creator A5035840384 @default.
• W4312882925 creator A5048170958 @default.
• W4312882925 creator A5070377160 @default.
• W4312882925 date "2022-01-01" @default.
• W4312882925 modified "2023-09-26" @default.
• W4312882925 title "Immunotherapy and Targeted Therapy in the Management of Oral Cancers" @default.
• W4312882925 cites W1514134885 @default.
• W4312882925 cites W2004630197 @default.
• W4312882925 cites W2007649418 @default.
• W4312882925 cites W2017712207 @default.
• W4312882925 cites W2028376975 @default.
• W4312882925 cites W2036882955 @default.
• W4312882925 cites W2049491375 @default.
• W4312882925 cites W2064047613 @default.
• W4312882925 cites W2077804275 @default.
• W4312882925 cites W2089349496 @default.
• W4312882925 cites W2090900427 @default.
• W4312882925 cites W2096735689 @default.
• W4312882925 cites W2099560139 @default.
• W4312882925 cites W2099804286 @default.
• W4312882925 cites W2107598346 @default.
• W4312882925 cites W2112845420 @default.
• W4312882925 cites W2118471749 @default.
• W4312882925 cites W2132020367 @default.
• W4312882925 cites W2152715911 @default.
• W4312882925 cites W2155464214 @default.
• W4312882925 cites W2343077206 @default.
• W4312882925 cites W2345568581 @default.
• W4312882925 cites W2396885039 @default.
• W4312882925 cites W2553051584 @default.
• W4312882925 cites W2580091136 @default.
• W4312882925 cites W2623774984 @default.
• W4312882925 cites W2739910629 @default.
• W4312882925 cites W2761376533 @default.
• W4312882925 cites W2761586559 @default.
• W4312882925 cites W2767336741 @default.
• W4312882925 cites W2769890966 @default.
• W4312882925 cites W2770997251 @default.
• W4312882925 cites W2774310031 @default.
• W4312882925 cites W2789897492 @default.
• W4312882925 cites W2794577178 @default.
• W4312882925 cites W2890158083 @default.
• W4312882925 cites W2890322466 @default.
• W4312882925 cites W2898092643 @default.
• W4312882925 cites W2900046418 @default.
• W4312882925 cites W2902690248 @default.
• W4312882925 cites W2911678709 @default.
• W4312882925 cites W2944013917 @default.
• W4312882925 cites W2944264995 @default.
• W4312882925 cites W2947216102 @default.
• W4312882925 cites W2965754895 @default.
• W4312882925 cites W2969648360 @default.
• W4312882925 cites W2992050889 @default.
• W4312882925 cites W3006664585 @default.
• W4312882925 cites W3028523516 @default.
• W4312882925 cites W3032907499 @default.
• W4312882925 cites W3034212817 @default.
• W4312882925 cites W3035383735 @default.
• W4312882925 cites W3035944244 @default.
• W4312882925 cites W3080936926 @default.
• W4312882925 cites W3084353392 @default.
• W4312882925 cites W3093811669 @default.
• W4312882925 cites W3116216573 @default.
• W4312882925 cites W3129917327 @default.
• W4312882925 cites W3157558500 @default.
• W4312882925 cites W3189201491 @default.
• W4312882925 cites W3197263234 @default.
• W4312882925 cites W3197555952 @default.
• W4312882925 cites W3198082969 @default.
• W4312882925 cites W3198709458 @default.
• W4312882925 cites W3203420675 @default.
• W4312882925 cites W4200117698 @default.
• W4312882925 cites W4214923989 @default.
• W4312882925 cites W4220679821 @default.
• W4312882925 cites W4240337585 @default.
• W4312882925 cites W4283706681 @default.
• W4312882925 doi "https://doi.org/10.1615/critrevoncog.2022046361" @default.
• W4312882925 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37199300" @default.
• W4312882925 hasPublicationYear "2022" @default.
• W4312882925 type Work @default.
• W4312882925 citedByCount "0" @default.
• W4312882925 crossrefType "journal-article" @default.
• W4312882925 hasAuthorship W4312882925A5033595890 @default.
• W4312882925 hasAuthorship W4312882925A5035840384 @default.
• W4312882925 hasAuthorship W4312882925A5048170958 @default.
• W4312882925 hasAuthorship W4312882925A5070377160 @default.
• W4312882925 hasConcept C121608353 @default.
• W4312882925 hasConcept C126322002 @default.
• W4312882925 hasConcept C159654299 @default.
• W4312882925 hasConcept C203014093 @default.
• W4312882925 hasConcept C2775949291 @default.
• W4312882925 hasConcept C2777381376 @default.
• W4312882925 hasConcept C2777701055 @default.
• W4312882925 hasConcept C2777742743 @default.
• W4312882925 hasConcept C2779438470 @default.

• next