FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312891306> ?p ?o ?g. }

• W4312891306 abstract "<b>Aim:</b> To assess the survival rate and risk factors associated with mortality in patients with non-CF bronchiectasis (NCFB). <b>Methods:</b> During 2014-2019 we prospectively enrolled HRCT confirmed adult NCFB patients in a single tertiary medical center. All patients were followed up for 36 months since study enrollment. Univariate and multivariate Cox proportional hazards models were generated to test the association between the potential clinical, imaging, microbiological and functional factors with the mortality risk in the study cohort. <b>Results:</b> A total of 401 NCFB patients (57±14 years, 57% men) were enrolled and followed up during the study period. The most common etiology types of the NCFB in the study patients were idiopathic (33%), post-TB (22%) and COPD related bronchiectasis (18%). A severe BSI score (≥9) was identified in 78% of the patients and pulmonary hypertension (PH) - in 35% of the cases. During the follow-up period 99 patients (25%) died. Multivariate Cox regression analysis identified an independent association with the risk of death of the following factors MRC dyspnea score (HR: 2.54; 95% CI: 1.83-3.5; p<0.0001); <i>Pseudomonas</i> colonization status (HR: 1.9; 95% CI: 1.19-3.0; p=0.006); age (HR: 1.03; 95% CI: 1.01-1.05; p= 0.001); HIV infection (HR: 8.31; 95% CI: 3.83-18.03; p<0.0001); ratio of the diameter of the main pulmonary arteria to the diameter of the ascending aorta on the HRCT (HR: 3.7; 95% CI: 1.09-12.83; p=0.03) and BMI (HR: 0.95; 95% CI: 0.92-0.99; p=0.02). <b>Conclusion:</b> Patients with imaging features of severe bronchiectasis has a significant risk of death, that being associated with more severe MRC score, <i>Pseudomonas</i> colonization, HIV infection, BMI and imaging signs of PH on HRCT." @default.
• W4312891306 created "2023-01-05" @default.
• W4312891306 creator A5022785159 @default.
• W4312891306 creator A5025245941 @default.
• W4312891306 creator A5033993249 @default.
• W4312891306 creator A5044612162 @default.
• W4312891306 creator A5082343053 @default.
• W4312891306 date "2022-09-04" @default.
• W4312891306 modified "2023-09-28" @default.
• W4312891306 title "Mortality related risk factors in patients with non-cystic fibrosis bronchiectasis" @default.
• W4312891306 doi "https://doi.org/10.1183/13993003.congress-2022.4014" @default.
• W4312891306 hasPublicationYear "2022" @default.
• W4312891306 type Work @default.
• W4312891306 citedByCount "0" @default.
• W4312891306 crossrefType "proceedings-article" @default.
• W4312891306 hasAuthorship W4312891306A5022785159 @default.
• W4312891306 hasAuthorship W4312891306A5025245941 @default.
• W4312891306 hasAuthorship W4312891306A5033993249 @default.
• W4312891306 hasAuthorship W4312891306A5044612162 @default.
• W4312891306 hasAuthorship W4312891306A5082343053 @default.
• W4312891306 hasConcept C126322002 @default.
• W4312891306 hasConcept C137627325 @default.
• W4312891306 hasConcept C188816634 @default.
• W4312891306 hasConcept C207103383 @default.
• W4312891306 hasConcept C2777714996 @default.
• W4312891306 hasConcept C2779379686 @default.
• W4312891306 hasConcept C38180746 @default.
• W4312891306 hasConcept C44249647 @default.
• W4312891306 hasConcept C50382708 @default.
• W4312891306 hasConcept C71924100 @default.
• W4312891306 hasConcept C90924648 @default.
• W4312891306 hasConceptScore W4312891306C126322002 @default.
• W4312891306 hasConceptScore W4312891306C137627325 @default.
• W4312891306 hasConceptScore W4312891306C188816634 @default.
• W4312891306 hasConceptScore W4312891306C207103383 @default.
• W4312891306 hasConceptScore W4312891306C2777714996 @default.
• W4312891306 hasConceptScore W4312891306C2779379686 @default.
• W4312891306 hasConceptScore W4312891306C38180746 @default.
• W4312891306 hasConceptScore W4312891306C44249647 @default.
• W4312891306 hasConceptScore W4312891306C50382708 @default.
• W4312891306 hasConceptScore W4312891306C71924100 @default.
• W4312891306 hasConceptScore W4312891306C90924648 @default.
• W4312891306 hasLocation W43128913061 @default.
• W4312891306 hasOpenAccess W4312891306 @default.
• W4312891306 hasPrimaryLocation W43128913061 @default.
• W4312891306 hasRelatedWork W1999097079 @default.
• W4312891306 hasRelatedWork W2113390168 @default.
• W4312891306 hasRelatedWork W2119576612 @default.
• W4312891306 hasRelatedWork W2565245769 @default.
• W4312891306 hasRelatedWork W2912705052 @default.
• W4312891306 hasRelatedWork W2987985474 @default.
• W4312891306 hasRelatedWork W3164121017 @default.
• W4312891306 hasRelatedWork W3174612885 @default.
• W4312891306 hasRelatedWork W4224304419 @default.
• W4312891306 hasRelatedWork W4311598218 @default.
• W4312891306 isParatext "false" @default.
• W4312891306 isRetracted "false" @default.
• W4312891306 workType "article" @default.