Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312896119> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4312896119 abstract "Abstract Introduction Varicose veins are prevalent throughout the UK population, affecting a third of adults. Various treatments exist and must be validated by rigorous testing. Randomised control trials (RCTs) are the accepted gold standard in the hierarchy of evidence, comparing the effectiveness of interventions. Poor recruitment is common among surgical trials and threatens their success. To ensure adequate participation, the underlying barriers to recruitment need to be identified. The objective of this study was to identify the reasons for refusal in four varicose vein RCTs. Secondary aims analysed patient characteristics to assess patient trends. Methods A qualitative survey was offered to eligible patients refusing recruitment, recording their reasons. Patients were identified and given an information leaflet before confirming a decision. Patient characteristics, demographics and themes were assessed using qualitative and statistical analysis. Ethical approval was not required. Results Overall, 115/429 of patients refused RCT participation and all (n=115) completed the survey. Patients mainly expressed refusal due to preferences for different treatments (25%) followed by employment commitments (14%). Follow-up procedures dissuade patients and anxiety was associated with patient characteristics. Females are more concerned about their autonomy (26.4%) whereas males express worry about external obligations (14.6%). Misunderstanding the severity of risks of treatments and varicose veins elevated concerns across both genders. Conclusion Unwillingness to participate is determined by individual circumstances, patient bias and altruism. Multiple factors influence decision making such as familial views and personal demographics. Creating a more robust recruitment process relies on encouraging the acceptance of clinical equipoise and targeting patient beliefs through enhanced communication and improving accessibility. Take-home message Patients undergoing recruitment into surgical trials are influenced by their ability to understand and recall information, patient preference and individual characteristics which are influenced by demographics such as anxiety and employment. Targeting these identified barriers to participation will improve accessibility into RCTs." @default.
- W4312896119 created "2023-01-05" @default.
- W4312896119 creator A5014485225 @default.
- W4312896119 creator A5032680564 @default.
- W4312896119 creator A5034554647 @default.
- W4312896119 creator A5063057837 @default.
- W4312896119 creator A5068892724 @default.
- W4312896119 date "2022-07-22" @default.
- W4312896119 modified "2023-09-29" @default.
- W4312896119 title "O078 Why do patients decline to participate in clinical trials? The view of potential participants having varicose vein treatments" @default.
- W4312896119 doi "https://doi.org/10.1093/bjs/znac242.078" @default.
- W4312896119 hasPublicationYear "2022" @default.
- W4312896119 type Work @default.
- W4312896119 citedByCount "0" @default.
- W4312896119 crossrefType "journal-article" @default.
- W4312896119 hasAuthorship W4312896119A5014485225 @default.
- W4312896119 hasAuthorship W4312896119A5032680564 @default.
- W4312896119 hasAuthorship W4312896119A5034554647 @default.
- W4312896119 hasAuthorship W4312896119A5063057837 @default.
- W4312896119 hasAuthorship W4312896119A5068892724 @default.
- W4312896119 hasConcept C118552586 @default.
- W4312896119 hasConcept C126322002 @default.
- W4312896119 hasConcept C139265228 @default.
- W4312896119 hasConcept C141071460 @default.
- W4312896119 hasConcept C144024400 @default.
- W4312896119 hasConcept C149923435 @default.
- W4312896119 hasConcept C159110408 @default.
- W4312896119 hasConcept C168563851 @default.
- W4312896119 hasConcept C1862650 @default.
- W4312896119 hasConcept C27415008 @default.
- W4312896119 hasConcept C2775919319 @default.
- W4312896119 hasConcept C2777475103 @default.
- W4312896119 hasConcept C2779978724 @default.
- W4312896119 hasConcept C2780084366 @default.
- W4312896119 hasConcept C2908647359 @default.
- W4312896119 hasConcept C512399662 @default.
- W4312896119 hasConcept C535046627 @default.
- W4312896119 hasConcept C558461103 @default.
- W4312896119 hasConcept C70410870 @default.
- W4312896119 hasConcept C71924100 @default.
- W4312896119 hasConcept C99454951 @default.
- W4312896119 hasConceptScore W4312896119C118552586 @default.
- W4312896119 hasConceptScore W4312896119C126322002 @default.
- W4312896119 hasConceptScore W4312896119C139265228 @default.
- W4312896119 hasConceptScore W4312896119C141071460 @default.
- W4312896119 hasConceptScore W4312896119C144024400 @default.
- W4312896119 hasConceptScore W4312896119C149923435 @default.
- W4312896119 hasConceptScore W4312896119C159110408 @default.
- W4312896119 hasConceptScore W4312896119C168563851 @default.
- W4312896119 hasConceptScore W4312896119C1862650 @default.
- W4312896119 hasConceptScore W4312896119C27415008 @default.
- W4312896119 hasConceptScore W4312896119C2775919319 @default.
- W4312896119 hasConceptScore W4312896119C2777475103 @default.
- W4312896119 hasConceptScore W4312896119C2779978724 @default.
- W4312896119 hasConceptScore W4312896119C2780084366 @default.
- W4312896119 hasConceptScore W4312896119C2908647359 @default.
- W4312896119 hasConceptScore W4312896119C512399662 @default.
- W4312896119 hasConceptScore W4312896119C535046627 @default.
- W4312896119 hasConceptScore W4312896119C558461103 @default.
- W4312896119 hasConceptScore W4312896119C70410870 @default.
- W4312896119 hasConceptScore W4312896119C71924100 @default.
- W4312896119 hasConceptScore W4312896119C99454951 @default.
- W4312896119 hasIssue "Supplement_4" @default.
- W4312896119 hasLocation W43128961191 @default.
- W4312896119 hasOpenAccess W4312896119 @default.
- W4312896119 hasPrimaryLocation W43128961191 @default.
- W4312896119 hasRelatedWork W2033287858 @default.
- W4312896119 hasRelatedWork W2034260405 @default.
- W4312896119 hasRelatedWork W2044565861 @default.
- W4312896119 hasRelatedWork W2072082708 @default.
- W4312896119 hasRelatedWork W2091778606 @default.
- W4312896119 hasRelatedWork W2609940642 @default.
- W4312896119 hasRelatedWork W2752357227 @default.
- W4312896119 hasRelatedWork W2947794053 @default.
- W4312896119 hasRelatedWork W4281816904 @default.
- W4312896119 hasRelatedWork W3096531094 @default.
- W4312896119 hasVolume "109" @default.
- W4312896119 isParatext "false" @default.
- W4312896119 isRetracted "false" @default.
- W4312896119 workType "article" @default.