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- W4312908721 abstract "<b>Introduction:</b> Lymphopenia is defined as a peripheral blood lymphocyte count <1500/mm3. It may be a predictive factor for clinical outcomes of COVID-19, including mortality. This study aims to explore the relationship between lymphocyte count and the severity of COVID-19. <b>Methods:</b> Retrospective study of hospitalized patients with COVID-19 (Moderate and Severe COVID-19 Pneumonia) in pneumology department D of Abderahman Mami hospital. We compared 2 groups: (G1) 197 patients with lymphopenia versus (G2): 100 patients without lymphopenia <b>Results:</b> The two groups were comparable with regard to the frequency of dyspnea (70% G1 vs 63%, p=0.05). Among the 197 patients in G1, 69.3% of patients were ≥60 years old vs 38% in G2, p=0.3. Comorbidities were similar between G1 and G2 (cardiovascular comorbidites: 43% G1 vs 52%G2 and respiratory comorbidites 21.8% G1 vs20% in G2). No significant difference was found between oxygen requirements (6.7L/min in G1 vs 5.1L/min in G2, p=0.2). There was a trend toward higher serum CRP and D-dimer levels in G1 (96% in G1 vs. 92% in G2, p=0.05 and 51% in G1 vs. 43% in G2, p=0.2 respectively). The prevalence of lung involvement >50% was 28.5% G1 vs 20.8%, p=0.1. Patients in groups G1 and G2 required non invasive ventilation and transfer to an intensive care unit in a comparable manner (30% in group 1 vs 22% in group 2, p=0.1). No significantly higher mortality rate was associated with lymphopenia (8.2% in G1 vs 6.8% in G 2, p=0.6). <b>Conclusion:</b> lymphopenia was not predictive of disease severity in COVID-19 patients in this study." @default.
- W4312908721 created "2023-01-05" @default.
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- W4312908721 date "2022-09-04" @default.
- W4312908721 modified "2023-09-26" @default.
- W4312908721 title "Is lymphopenia a predictive factor of outcomes in COVID-19 patients?" @default.
- W4312908721 doi "https://doi.org/10.1183/13993003.congress-2022.3922" @default.
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