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- W4312910715 abstract "Acute kidney injury (AKI) is the sudden deterioration of kidney function, which causes a decrease in the glomerular filtration rate. Neonatal acute kidney injury is common in neonates admitted to neonatal intensive care units (NICU) and is a major factor for neonatal mortality and morbidity. The incidence of AKI is 6-24% in NICU neonates, 25% in oliguric forms, 60% in non-oliguric forms and 15% in anuric forms. AKI occurs more frequently in very low birth weight babies. The diagnosis involves family and perinatal history, physical examination of the newborn, biochemical examinations, blood gas analysis, hematological examination, urine measurements, imaging studies and histological studies. Prophylaxis is preferable to curative treatment, and involves early detection of risk factors, fetal ultrasound to detect renal malformations, prevention of decreased renal blood flow or intravascular blood volume by prophylactic administration of dopamine and furosemide or mannitol, along with avoidance of nephrotoxic drugs during pregnancy. Neonatal dialysis in newborns and children who have reduced muscle mass is done at lower values of serum creatinine. Hemodialysis has been replaced by peritoneal dialysis and hemodiafiltration, the technique of choice for the treatment of vascular overload. Peritoneal dialysis is contraindicated in newborns with respiratory distress, shock, peritonitis or ulceronecrotic enterocolitis. Knowing and using standardized definitions and staging of AKI in newborn contribute to a more efficient approach to the patient by the complex medical team." @default.
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- W4312910715 date "2022-01-01" @default.
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- W4312910715 title "Acute kidney injury in the newborn – a challenge for the medical team" @default.
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- W4312910715 doi "https://doi.org/10.26416/pedi.67.3.2022.7231" @default.
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