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- W4312960462 abstract "<b>Background:</b> The prevalence of allergic diseases has increased for decades, but the recent trends are less known. <b>Aim:</b> To compare the trends in prevalence of allergic sensitization, asthma and rhinitis among children from 1996 to 2017, and to evaluate the association between allergic sensitization and asthma and rhinitis. <b>Methods:</b> Three cohorts of children (age 7-8 years) were invited to a parental questionnaire survey and skin prick testing (SPT) for ten common airborne allergens in 1996, 2006 and 2017. Participation rate was 2148 (88%), 1693 (89%), and 1762 (87%), respectively. <b>Results:</b> The prevalence of any positive SPT was 21% in 1996, and 30% both in 2006 and 2017, p<0.001. The pattern of sensitization was similar all three years. The prevalence of physician-diagnosed asthma increased from 6.4% (1996) to 7.2% (2006) and 12.5% (2017), p<0.001, while the corresponding prevalence for physician-diagnosed rhinitis decreased from 7.3% in 1996 to 5.4% in 2017, p=0.013. The prevalence of wheeze and rhinitis symptoms was around 11% and 15%, respectively, in all surveys. The association between allergic sensitization and physician-diagnosed asthma became weaker by time; RR 2.9 in 1996 and 2.1 in 2017, while the RRs for the association with physician-diagnosed rhinitis increased from 9.4 to 14.2. <b>Conclusion:</b> Despite the strong association between allergic sensitization and asthma and rhinitis, the prevalence trends over 20 years were not parallel. The different trends in clinical outcomes suggest diagnostic changes and increased awareness, but needs further investigations." @default.
- W4312960462 created "2023-01-05" @default.
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- W4312960462 date "2022-09-04" @default.
- W4312960462 modified "2023-10-03" @default.
- W4312960462 title "Different prevalence trends in allergic sensitization, asthma and rhinitis among children from 1996 to 2017 in Northern Sweden" @default.
- W4312960462 doi "https://doi.org/10.1183/13993003.congress-2022.3134" @default.
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