Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313009145> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4313009145 endingPage "609" @default.
- W4313009145 startingPage "606" @default.
- W4313009145 abstract "In articles and chapters on the subject of acoustic neuroma, it is almost invariably stated that they are well-encapsulated tumors. During surgical procedures, blunt mechanical dissection defines a natural subsurface cleavage plane that leaves intact a several millimeter thick rind of tumor surface. Occasionally, as a concession to neural integrity, less than complete resection is elected, leaving behind this “capsular” remnant. To clarify the nature of the surface of acoustic neuromas and to test whether this long held description is indeed correct, a microscopic analysis of 10 surgical specimens was performed. A wedge was harvested from the free surface of the tumor in the mid cerebellopontine angle that included a large, undisturbed section of the tumor surface. Histologic analysis showed that for most of the tumor surface only an extremely thin (3 to 5 μm) layer of connective tissue envelops the tumor. Neoplastic Schwann cells, which extend essentially to the margin of the tumor, were found to be somewhat flattened and compressed in the vicinity of the surface. Although acoustic neuromas are surrounded by a continuous layer of connective tissue, it is so exceptionally thin (on average less than the diameter of a red blood cell) that its edge cannot be visualized intraoperatively by a surgeon. Because the pathologic definition of a capsule is a thick, enveloping layer of connective tissue that is both micro- and macroscopically evident, it must be concluded that acoustic neuromas are nonencapsulated, at least in the conventional sense of the term. The surface peel observed intraoperatively is surgically produced during tumor debulking by cleaving of the looser central component from the more compressed portion of neoplastic cells that lies immediately beneath the free margin of the lesion." @default.
- W4313009145 created "2023-01-05" @default.
- W4313009145 creator A5002279065 @default.
- W4313009145 creator A5004915384 @default.
- W4313009145 creator A5022643612 @default.
- W4313009145 creator A5052136063 @default.
- W4313009145 creator A5085383790 @default.
- W4313009145 date "1997-12-01" @default.
- W4313009145 modified "2023-09-26" @default.
- W4313009145 title "Are Acoustic Neuromas Encapsulated Tumors?" @default.
- W4313009145 cites W1968208476 @default.
- W4313009145 cites W1985308649 @default.
- W4313009145 cites W1986556404 @default.
- W4313009145 cites W2004785692 @default.
- W4313009145 cites W2051568604 @default.
- W4313009145 cites W2070218610 @default.
- W4313009145 cites W2077538909 @default.
- W4313009145 cites W2077956333 @default.
- W4313009145 cites W2093211583 @default.
- W4313009145 cites W2099374955 @default.
- W4313009145 cites W2116657732 @default.
- W4313009145 cites W2149126188 @default.
- W4313009145 cites W2283690437 @default.
- W4313009145 cites W2289310561 @default.
- W4313009145 cites W4252793238 @default.
- W4313009145 doi "https://doi.org/10.1016/s0194-59989770040-8" @default.
- W4313009145 hasPublicationYear "1997" @default.
- W4313009145 type Work @default.
- W4313009145 citedByCount "5" @default.
- W4313009145 countsByYear W43130091452022 @default.
- W4313009145 countsByYear W43130091452023 @default.
- W4313009145 crossrefType "journal-article" @default.
- W4313009145 hasAuthorship W4313009145A5002279065 @default.
- W4313009145 hasAuthorship W4313009145A5004915384 @default.
- W4313009145 hasAuthorship W4313009145A5022643612 @default.
- W4313009145 hasAuthorship W4313009145A5052136063 @default.
- W4313009145 hasAuthorship W4313009145A5085383790 @default.
- W4313009145 hasConcept C105702510 @default.
- W4313009145 hasConcept C141071460 @default.
- W4313009145 hasConcept C142724271 @default.
- W4313009145 hasConcept C192562407 @default.
- W4313009145 hasConcept C2778934081 @default.
- W4313009145 hasConcept C518705261 @default.
- W4313009145 hasConcept C71924100 @default.
- W4313009145 hasConceptScore W4313009145C105702510 @default.
- W4313009145 hasConceptScore W4313009145C141071460 @default.
- W4313009145 hasConceptScore W4313009145C142724271 @default.
- W4313009145 hasConceptScore W4313009145C192562407 @default.
- W4313009145 hasConceptScore W4313009145C2778934081 @default.
- W4313009145 hasConceptScore W4313009145C518705261 @default.
- W4313009145 hasConceptScore W4313009145C71924100 @default.
- W4313009145 hasIssue "6" @default.
- W4313009145 hasLocation W43130091451 @default.
- W4313009145 hasOpenAccess W4313009145 @default.
- W4313009145 hasPrimaryLocation W43130091451 @default.
- W4313009145 hasRelatedWork W1990531813 @default.
- W4313009145 hasRelatedWork W1995156228 @default.
- W4313009145 hasRelatedWork W2047753131 @default.
- W4313009145 hasRelatedWork W2082751488 @default.
- W4313009145 hasRelatedWork W2107105584 @default.
- W4313009145 hasRelatedWork W2408847797 @default.
- W4313009145 hasRelatedWork W2468077122 @default.
- W4313009145 hasRelatedWork W2899084033 @default.
- W4313009145 hasRelatedWork W3094404303 @default.
- W4313009145 hasRelatedWork W4255664071 @default.
- W4313009145 hasVolume "117" @default.
- W4313009145 isParatext "false" @default.
- W4313009145 isRetracted "false" @default.
- W4313009145 workType "article" @default.