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• W4313040826 abstract "Protein organization and function can be looked at as originating from a combination of a small subset of domains each carrying an independent modular function. Although many domain families exist that mediate protein interaction, for historical reasons the characterization of SRC homology domains SH2 and SH3 has laid the foundation for a new way of thinking about cell organization and yielded a framework for the discovery and analysis of a much larger family of interaction domains. SH2 domains bind proteins carrying phospho-tyrosines and therefore offer a mechanism for protein to sense changes caused by signals that modulate phosphorylation of tyrosines." @default.
• W4313040826 created "2023-01-06" @default.
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• W4313040826 date "2016-01-01" @default.
• W4313040826 modified "2023-09-25" @default.
• W4313040826 title "SH3 and SH2: Prototypic Domains to Mediate Regulatory Mechanisms in the Cell" @default.
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• W4313040826 doi "https://doi.org/10.1016/b978-0-12-821618-7.30013-x" @default.
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