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- W4313060256 abstract "Methoprene is a non-cyclic synthetic terpenoid established since 1970s as a generic insecticide. Although it has been widely used for the control of several pests, toxic effects on non-target organisms, like crustaceans and fishes, have been reported. In the late 1990s, a possible relationship between the use of methoprene and an increase of malformed amphibians in North America was proposed, though later dismissed. This fact, along with the observation that methoprene and its derivatives may stimulate gene transcription in vertebrates by acting through the retinoic acid-responsive transcription factors, activating the retinoid X receptors (RXRs), drew especially attention to this compound. However, drastic ecotoxicological effects assigned to this compound have consecutively been downplayed and it is consensual at this point that toxicity to humans is limited." @default.
- W4313060256 created "2023-01-06" @default.
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- W4313060256 date "2022-01-01" @default.
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- W4313060256 title "Methoprene" @default.
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- W4313060256 doi "https://doi.org/10.1016/b978-0-12-824315-2.00197-4" @default.
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