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- W4313140588 abstract "Knowledge of the bio-macromolecules adsorption on polylactide (PLA) was essential to the application of PLA-based biomedical materials. This study presented the adsorption behavior of type I collagen on control (CH 3 -enriched) and modified (introduced COOH– and CONH 2 – respectively) PLA surfaces by quartz crystal microbalance with energy dissipation measurements (QCM-D) and atomic force microscopy (AFM). The results showed that the Langmuir adsorption isotherms were obtained, indicating a monomolecular layer adsorption of collagen on PLA coatings. Adsorption of collagen could reach equilibrium more quickly on the modified surfaces than on the control. Large amounts of collagen (1522.2 ng·cm −2 ) was assembled tightly on the COOH-enriched surface of PLA, owing to the electrostatic attracting. However it was inhibited on the CONH 2 -enriched surface because of its increasing hydrophilicity. A netlike structure was formed on the control and COOH-enriched surfaces, while only a few of braching fibril was found on the CONH 2 -enriched surface. The behaviour of protein adsorption on the surfaces with different groups might effect the next stage of cell adhesion on scaffold." @default.
- W4313140588 created "2023-01-06" @default.
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- W4313140588 date "2022-07-01" @default.
- W4313140588 modified "2023-09-27" @default.
- W4313140588 title "Type I Collagen Adsorption Behavior on the Control and Modified Surface of Polylactide Coating" @default.
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- W4313140588 doi "https://doi.org/10.1166/sam.2022.4322" @default.
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