Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313142019> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W4313142019 endingPage "1170" @default.
- W4313142019 startingPage "1166" @default.
- W4313142019 abstract "The formulation of only moderately water-soluble pharmaceuticals can benefit from the incorporation of nanoparticles, which increases the drugs’ bioavailability. The primary objective of this work was to create and evaluate fluvastatin-loaded nanoparticles using the precipitation process to improve their solubility and bioavailability. Precipitation was used to prepare fluvastatin nanoparticles, which are classified as a BCS class II drug. These particles were then characterized using techniques such as Fourier transform infrared spectroscopy, differential scanning calorimetry, powder X-ray diffraction, scanning electron microscopy, zeta potential, and in-vitro drug release studies. There was no evidence of contact between the drug and the polymers based on the differential scanning calorimetry results, powder X-ray diffractometry, and Fourier transforms infrared spectroscopy. Images obtained by scanning electron microscopy revealed that the nanoparticles had a spherical form. The fact that the water solubility of drug-loaded nanoparticles was increased in comparison to the pure drug and that they displayed an improved dissolution profile was evidence that nanoprecipitation was a straightforward and accurate process. Both this technology on a laboratory scale and this strategy could be used to improve the solubility and bioavailability of BCS class II medications." @default.
- W4313142019 created "2023-01-06" @default.
- W4313142019 creator A5009521778 @default.
- W4313142019 creator A5017293613 @default.
- W4313142019 creator A5026759436 @default.
- W4313142019 creator A5052447522 @default.
- W4313142019 creator A5059575434 @default.
- W4313142019 creator A5061904874 @default.
- W4313142019 creator A5072999734 @default.
- W4313142019 creator A5073264332 @default.
- W4313142019 date "2022-06-30" @default.
- W4313142019 modified "2023-10-01" @default.
- W4313142019 title "Formulation and Evaluation of Fluvastatib-loaded Nanoparticles by Nanoprecepitration Method" @default.
- W4313142019 doi "https://doi.org/10.25258/ijddt.12.3.40" @default.
- W4313142019 hasPublicationYear "2022" @default.
- W4313142019 type Work @default.
- W4313142019 citedByCount "0" @default.
- W4313142019 crossrefType "journal-article" @default.
- W4313142019 hasAuthorship W4313142019A5009521778 @default.
- W4313142019 hasAuthorship W4313142019A5017293613 @default.
- W4313142019 hasAuthorship W4313142019A5026759436 @default.
- W4313142019 hasAuthorship W4313142019A5052447522 @default.
- W4313142019 hasAuthorship W4313142019A5059575434 @default.
- W4313142019 hasAuthorship W4313142019A5061904874 @default.
- W4313142019 hasAuthorship W4313142019A5072999734 @default.
- W4313142019 hasAuthorship W4313142019A5073264332 @default.
- W4313142019 hasBestOaLocation W43131420191 @default.
- W4313142019 hasConcept C121332964 @default.
- W4313142019 hasConcept C127413603 @default.
- W4313142019 hasConcept C13965031 @default.
- W4313142019 hasConcept C14631669 @default.
- W4313142019 hasConcept C155574463 @default.
- W4313142019 hasConcept C155672457 @default.
- W4313142019 hasConcept C159985019 @default.
- W4313142019 hasConcept C160892712 @default.
- W4313142019 hasConcept C171250308 @default.
- W4313142019 hasConcept C178790620 @default.
- W4313142019 hasConcept C181389837 @default.
- W4313142019 hasConcept C185592680 @default.
- W4313142019 hasConcept C192562407 @default.
- W4313142019 hasConcept C26771246 @default.
- W4313142019 hasConcept C39519442 @default.
- W4313142019 hasConcept C42360764 @default.
- W4313142019 hasConcept C71924100 @default.
- W4313142019 hasConcept C86181022 @default.
- W4313142019 hasConcept C88380143 @default.
- W4313142019 hasConcept C97355855 @default.
- W4313142019 hasConcept C98274493 @default.
- W4313142019 hasConceptScore W4313142019C121332964 @default.
- W4313142019 hasConceptScore W4313142019C127413603 @default.
- W4313142019 hasConceptScore W4313142019C13965031 @default.
- W4313142019 hasConceptScore W4313142019C14631669 @default.
- W4313142019 hasConceptScore W4313142019C155574463 @default.
- W4313142019 hasConceptScore W4313142019C155672457 @default.
- W4313142019 hasConceptScore W4313142019C159985019 @default.
- W4313142019 hasConceptScore W4313142019C160892712 @default.
- W4313142019 hasConceptScore W4313142019C171250308 @default.
- W4313142019 hasConceptScore W4313142019C178790620 @default.
- W4313142019 hasConceptScore W4313142019C181389837 @default.
- W4313142019 hasConceptScore W4313142019C185592680 @default.
- W4313142019 hasConceptScore W4313142019C192562407 @default.
- W4313142019 hasConceptScore W4313142019C26771246 @default.
- W4313142019 hasConceptScore W4313142019C39519442 @default.
- W4313142019 hasConceptScore W4313142019C42360764 @default.
- W4313142019 hasConceptScore W4313142019C71924100 @default.
- W4313142019 hasConceptScore W4313142019C86181022 @default.
- W4313142019 hasConceptScore W4313142019C88380143 @default.
- W4313142019 hasConceptScore W4313142019C97355855 @default.
- W4313142019 hasConceptScore W4313142019C98274493 @default.
- W4313142019 hasIssue "03" @default.
- W4313142019 hasLocation W43131420191 @default.
- W4313142019 hasOpenAccess W4313142019 @default.
- W4313142019 hasPrimaryLocation W43131420191 @default.
- W4313142019 hasRelatedWork W2027424735 @default.
- W4313142019 hasRelatedWork W2084882873 @default.
- W4313142019 hasRelatedWork W2096309345 @default.
- W4313142019 hasRelatedWork W2118623650 @default.
- W4313142019 hasRelatedWork W2899714901 @default.
- W4313142019 hasRelatedWork W3006308228 @default.
- W4313142019 hasRelatedWork W3185495557 @default.
- W4313142019 hasRelatedWork W4366587409 @default.
- W4313142019 hasRelatedWork W2182366825 @default.
- W4313142019 hasRelatedWork W2475013518 @default.
- W4313142019 hasVolume "12" @default.
- W4313142019 isParatext "false" @default.
- W4313142019 isRetracted "false" @default.
- W4313142019 workType "article" @default.