Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313143282> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W4313143282 abstract "<h3>Introduction/Background</h3> The standard procedure in cervical cancer is radical hysterectomy (RH) and pelvic lymphadenectomy (PLND). Because of the increasing age of women at childbirth, fertility becomes a major challenge. We present 20 years of experience with two-step less radical fertility-sparing surgery in women with IA1, LVSI positive, IA2 and IB1 (<2 cm, infiltration less than half of stromal invasions. <h3>Methodology</h3> Preoperative workout consisted of histopathological diagnosis and magnetic resonance imaging along with ultrasonographic volumetry. We then performed laparoscopic sentinel lymph node mapping (SLNM) with frozen section (FS) followed by PLND and ‘selective parametrectomy’ (removal of afferent lymphatic channels from the paracervix) in case of a negative result. If verified by definitive histopathology, patients were treated by simple trachelectomy (IB1) or large cone (IA1/IA2) biopsy 1 week after primary surgery. <h3>Results</h3> From 1999 to 2018, 91 women were enrolled in the study (median age 29.1 years, range 21–40). Of these 91 women, 51 (56.0%) were nulliparous. The detection rate of SLNs was 100% per patient and the specific side detection rate 96.7%. Positive lymph nodes were diagnosed in nine cases (9.8%). These women then underwent RH. Fertility was spared in 80 women but 4 recurred locally (5.0%). The mortality rate was 0.0%. The median follow-up was 149 months. <h3>Conclusion</h3> Less radical fertility-sparing surgery with SLNM is safe in cervical cancers <2 cm at the largest diameter and infiltrating less than half of the cervical stroma. The recurrence rate is acceptable with no mortality. Morbidity with this procedure is low. Extended and accurate follow-up is necessary and human papillomavirus – high risk (HPV-HR tests seem to be useful in such follow-up assessment." @default.
- W4313143282 created "2023-01-06" @default.
- W4313143282 creator A5015678973 @default.
- W4313143282 creator A5042117256 @default.
- W4313143282 creator A5044288400 @default.
- W4313143282 creator A5047830770 @default.
- W4313143282 creator A5059654394 @default.
- W4313143282 creator A5065943539 @default.
- W4313143282 creator A5067211260 @default.
- W4313143282 date "2022-10-01" @default.
- W4313143282 modified "2023-09-26" @default.
- W4313143282 title "2022-RA-771-ESGO Twenty years of experience with less radical fertility-sparing surgery in early-stage cervical cancer" @default.
- W4313143282 doi "https://doi.org/10.1136/ijgc-2022-esgo.57" @default.
- W4313143282 hasPublicationYear "2022" @default.
- W4313143282 type Work @default.
- W4313143282 citedByCount "0" @default.
- W4313143282 crossrefType "proceedings-article" @default.
- W4313143282 hasAuthorship W4313143282A5015678973 @default.
- W4313143282 hasAuthorship W4313143282A5042117256 @default.
- W4313143282 hasAuthorship W4313143282A5044288400 @default.
- W4313143282 hasAuthorship W4313143282A5047830770 @default.
- W4313143282 hasAuthorship W4313143282A5059654394 @default.
- W4313143282 hasAuthorship W4313143282A5065943539 @default.
- W4313143282 hasAuthorship W4313143282A5067211260 @default.
- W4313143282 hasBestOaLocation W43131432821 @default.
- W4313143282 hasConcept C121608353 @default.
- W4313143282 hasConcept C126322002 @default.
- W4313143282 hasConcept C126838900 @default.
- W4313143282 hasConcept C141071460 @default.
- W4313143282 hasConcept C146357865 @default.
- W4313143282 hasConcept C151730666 @default.
- W4313143282 hasConcept C2776874909 @default.
- W4313143282 hasConcept C2778220009 @default.
- W4313143282 hasConcept C2780824555 @default.
- W4313143282 hasConcept C2780849966 @default.
- W4313143282 hasConcept C2908647359 @default.
- W4313143282 hasConcept C2910227796 @default.
- W4313143282 hasConcept C518429986 @default.
- W4313143282 hasConcept C71924100 @default.
- W4313143282 hasConcept C86803240 @default.
- W4313143282 hasConcept C99454951 @default.
- W4313143282 hasConceptScore W4313143282C121608353 @default.
- W4313143282 hasConceptScore W4313143282C126322002 @default.
- W4313143282 hasConceptScore W4313143282C126838900 @default.
- W4313143282 hasConceptScore W4313143282C141071460 @default.
- W4313143282 hasConceptScore W4313143282C146357865 @default.
- W4313143282 hasConceptScore W4313143282C151730666 @default.
- W4313143282 hasConceptScore W4313143282C2776874909 @default.
- W4313143282 hasConceptScore W4313143282C2778220009 @default.
- W4313143282 hasConceptScore W4313143282C2780824555 @default.
- W4313143282 hasConceptScore W4313143282C2780849966 @default.
- W4313143282 hasConceptScore W4313143282C2908647359 @default.
- W4313143282 hasConceptScore W4313143282C2910227796 @default.
- W4313143282 hasConceptScore W4313143282C518429986 @default.
- W4313143282 hasConceptScore W4313143282C71924100 @default.
- W4313143282 hasConceptScore W4313143282C86803240 @default.
- W4313143282 hasConceptScore W4313143282C99454951 @default.
- W4313143282 hasLocation W43131432821 @default.
- W4313143282 hasOpenAccess W4313143282 @default.
- W4313143282 hasPrimaryLocation W43131432821 @default.
- W4313143282 hasRelatedWork W1982515162 @default.
- W4313143282 hasRelatedWork W2014812463 @default.
- W4313143282 hasRelatedWork W2046705078 @default.
- W4313143282 hasRelatedWork W2372996503 @default.
- W4313143282 hasRelatedWork W2405908668 @default.
- W4313143282 hasRelatedWork W2431685244 @default.
- W4313143282 hasRelatedWork W2469255052 @default.
- W4313143282 hasRelatedWork W2480425062 @default.
- W4313143282 hasRelatedWork W2956054768 @default.
- W4313143282 hasRelatedWork W4230719942 @default.
- W4313143282 isParatext "false" @default.
- W4313143282 isRetracted "false" @default.
- W4313143282 workType "article" @default.