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- W4313155392 abstract "Background: The study aims to evaluate left-sided portal hypertension development and estimate the effect of long-term outcomes for resected pancreatic cancer patients according to splenic vein (SV) preservation. Methods: 94 patients who underwent pancreaticoduodenectomy (PD) for pancreatic cancer were enrolled in the study. The patients were divided into 2 groups according to SV preserving. (SV ligation group vs. SV preserving group) 47 patients were allocated into SV ligation group and SV preserving group each. Their spleen volume was calculated and compared serially. (preoperation, POM (postoperative month) 6, POM 12 and POM 24) In addition, their survival outcome, including disease-free survival (DFS) and overall survival (OS) were analyzed. Results: There was no significant difference of spleen volume between the 2 groups before PD. (SV ligation vs. SV preserving: 144.1 mL vs. 164.0 mL, p=0.352) However, 1 year after PD, the spleen volume of SV ligation group was significantly larger than that of the SV preserving group. (SV ligation vs. SV preserving: 235.4 mL vs. 163.6 mL, p=0.003) 1 patient who was in SV ligation group experienced gastric variceal bleeding. In the survival analysis, there were no significant differences between the 2 groups. (DFS: SV ligation vs. SV preserving, 11.0 months [8.8-13.2] vs. 12.0 months [11.0-13.0], p-value=0.992; OS: SV ligation vs. SV preserving, 32.0 months [10.4-53.6] vs. 44.0 months [16.3-71.7], p-value=0.659) Conclusion: Although SV ligation during the PD cause left-sided portal hypertension, it did not affect survival outcomes for pancreatic cancer patients.Tabled 1EP02D-105Preop. (mL)p-value6 months (mL)p-value12 months (mL)p-value24 months (mL)p-valueSV ligation144.10.352226.00.087235.40.003248.30.531SV preserving164.0184.3163.6211.2 Open table in a new tab" @default.
- W4313155392 created "2023-01-06" @default.
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- W4313155392 date "2022-01-01" @default.
- W4313155392 modified "2023-09-30" @default.
- W4313155392 title "Left-sided Portal Hypertension and its Outcomes after Pancreaticoduodenectomy According to Resection of the Splenic Vein for Pancreatic Cancer" @default.
- W4313155392 doi "https://doi.org/10.1016/j.hpb.2022.05.790" @default.
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