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- W4313161780 abstract "Novel drug delivery systems are the need of the hour due to the ineffectiveness of conventional dosage forms in conforming to a desirable profile in terms of site-specificity and drug release. Dextran serves as one of the most viable macromolecular carrier candidates for targeted drug delivery strategies owing to its excellent physicochemical chattels, allowing it to be endowed with various layers of specificity for enhancing its targeting potential. Dextran, a branched poly-α-d-glucoside, is a non-toxic, complex, biodegradable, and non-immunogenic polysaccharide. Interestingly, dextran carriers have a notable role in ameliorating the health of patients suffering from numerous chronic diseases, as the conventional delivery systems yield rapid clearance of drugs from the body resulting in momentary relief. This chapter is a sincere attempt at reviewing the versatile properties of dextran-based nano-carrier platforms and their application in drug delivery, with special emphasis on its preclinical and clinical studies." @default.
- W4313161780 created "2023-01-06" @default.
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- W4313161780 date "2022-01-01" @default.
- W4313161780 modified "2023-09-27" @default.
- W4313161780 title "Chapter 6. Dextran in the Delivery of Therapeutics: Chronicle of the Journey from Preclinical to Clinical Trials" @default.
- W4313161780 doi "https://doi.org/10.1039/9781839166235-00172" @default.
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