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- W4313198879 abstract "It has been a long-term goal to develop cancer-imaging techniques that have sufficient specificity and sensitivity, since early detection and complete resection are an important prognosticator for cancer treatment. Since fluorescence-guided diagnosis is one of the most powerful techniques for real-time in situ cancer detection, we have focused on developing a cancer-imaging method with activatable fluorescent probes targeted to enzymes that are overexpressed in cancer. These include probes for cancer-associated aminopeptidases, carboxypeptidases, and glycosidases, which allowed us to visualize certain types of cancers in the resected clinical specimens from the patients. In this presentation, I would like to introduce the molecular design, our recent effort for screening the candidate probes from our probe library, and its application for clinical specimens. We hope that fluorescence-guided diagnosis by our activatable probes can be used as an imaging guidance during surgical procedures to help surgeons for efficient tumor inspection." @default.
- W4313198879 created "2023-01-06" @default.
- W4313198879 creator A5023056922 @default.
- W4313198879 date "2022-01-01" @default.
- W4313198879 modified "2023-09-27" @default.
- W4313198879 title "Activatable fluorescence probes for rapid cancer imaging" @default.
- W4313198879 doi "https://doi.org/10.1254/jpssuppl.96.0_2-b-s14-3" @default.
- W4313198879 hasPublicationYear "2022" @default.
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