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- W4313201570 endingPage "105403" @default.
- W4313201570 startingPage "105403" @default.
- W4313201570 abstract "The genus Piper, a member of the Piperaceae family, comprises >2000 species, of which many are well known to possess considerable economic and medicinal values. Lignans are essential ingredients and are rich in Piper plants. Although many phytochemical studies have reported many lignans identified from Piper plants, comprehensive research has not reviewed these compounds. Hence, the present review reports on natural lignans from the genus Piper and their pharmacological activities. At least 275 lignans have been discovered from the Piper genus until October 2022, including traditional lignans, neolignans, oxyneolignans, norlignans, secolignans, and polyneolignans, especially some neolignans and norlignans with novel and complex scaffolds. In addition, these lignans have been reported to show various pharmacological activities, such as antimicrobial, anti-inflammatory, neuroprotective, antioxidative, anti-platelet aggregation, cytotoxic, anti-parasitic, CYP3A4 inhibitory activities, and so on. The current work presents an up-to-date critical review and a systematic summary of publications on lignans from the genus Piper to lay the groundwork and show better insights for further investigations." @default.
- W4313201570 created "2023-01-06" @default.
- W4313201570 creator A5010030908 @default.
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- W4313201570 creator A5053098274 @default.
- W4313201570 creator A5072861069 @default.
- W4313201570 creator A5075223313 @default.
- W4313201570 date "2023-03-01" @default.
- W4313201570 modified "2023-10-16" @default.
- W4313201570 title "Lignans from the genus Piper L. and their pharmacological activities: An updated review" @default.
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