FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313201977> ?p ?o ?g. }

• W4313201977 endingPage "9" @default.
• W4313201977 startingPage "1" @default.
• W4313201977 abstract "Dual antiplatelet therapy (DAPT) is the gold standard after acute coronary syndromes (ACS) or chronic coronary syndromes (CCS) undergoing percutaneous coronary intervention (PCI). Because local and systemic ischemic complications can occur particularly in the early phase (i.e. 1-3 months) after ACS or PCI, the synergistic platelet inhibition of aspirin and a P2Y12 inhibitor is of the utmost importance in this early phase. Moreover, the use of the more potent P2Y12 inhibitors prasugrel and ticagrelor have shown to further reduce the incidence of ischemic events compared to clopidogrel after an ACS. On the other hand, prolonged and potent antiplatelet therapy are inevitably associated with increased bleeding, which unlike thrombotic risk, tends to be stable over time and may outweigh the benefit of reducing ischemic events in these patients. The duration and composition of antiplatelet therapy remains a topic of debate in cardiology due to competing ischemic and bleeding risks, with guidelines and recommendations considerably evolving in the past years. An emerging strategy, called de-escalation, consisting in the administration of a less intense antithrombotic therapy after a short course of standard DAPT, has shown to reduce bleeding without any trade-off in ischemic events. De-escalation may be achieved with different antithrombotic strategies and can be either unguided or guided by platelet function or genetic testing. The aim of this review is to summarize the evidence and provide practical recommendations on the use of different de-escalation strategies in patients with ACS and CCS." @default.
• W4313201977 created "2023-01-06" @default.
• W4313201977 creator A5002872853 @default.
• W4313201977 creator A5010470244 @default.
• W4313201977 creator A5015687443 @default.
• W4313201977 creator A5033442682 @default.
• W4313201977 creator A5034263662 @default.
• W4313201977 creator A5037695205 @default.
• W4313201977 creator A5039638412 @default.
• W4313201977 creator A5046431472 @default.
• W4313201977 creator A5046904043 @default.
• W4313201977 creator A5051587096 @default.
• W4313201977 creator A5063343500 @default.
• W4313201977 creator A5088161654 @default.
• W4313201977 date "2023-04-01" @default.
• W4313201977 modified "2023-10-16" @default.
• W4313201977 title "De-escalation of antiplatelet therapy in patients with coronary artery disease: Time to change our strategy?" @default.
• W4313201977 cites W146673325 @default.
• W4313201977 cites W1553345686 @default.
• W4313201977 cites W1993518253 @default.
• W4313201977 cites W2081613030 @default.
• W4313201977 cites W2087951913 @default.
• W4313201977 cites W2103798714 @default.
• W4313201977 cites W2117559770 @default.
• W4313201977 cites W2121205446 @default.
• W4313201977 cites W2122594641 @default.
• W4313201977 cites W2169387542 @default.
• W4313201977 cites W2219664444 @default.
• W4313201977 cites W2431546415 @default.
• W4313201977 cites W2509918966 @default.
• W4313201977 cites W2614154720 @default.
• W4313201977 cites W2647552175 @default.
• W4313201977 cites W2743957957 @default.
• W4313201977 cites W2748517697 @default.
• W4313201977 cites W2754054868 @default.
• W4313201977 cites W2791681266 @default.
• W4313201977 cites W2792735509 @default.
• W4313201977 cites W2888458270 @default.
• W4313201977 cites W2895104863 @default.
• W4313201977 cites W2949986921 @default.
• W4313201977 cites W2951424940 @default.
• W4313201977 cites W2953479758 @default.
• W4313201977 cites W2953934063 @default.
• W4313201977 cites W2955952534 @default.
• W4313201977 cites W2971992346 @default.
• W4313201977 cites W2976166882 @default.
• W4313201977 cites W2980596005 @default.
• W4313201977 cites W2981795354 @default.
• W4313201977 cites W2982475069 @default.
• W4313201977 cites W3000394837 @default.
• W4313201977 cites W3011371150 @default.
• W4313201977 cites W3035351100 @default.
• W4313201977 cites W3036328220 @default.
• W4313201977 cites W3046725027 @default.
• W4313201977 cites W3080963011 @default.
• W4313201977 cites W3082881918 @default.
• W4313201977 cites W3087046564 @default.
• W4313201977 cites W3094217864 @default.
• W4313201977 cites W3095655289 @default.
• W4313201977 cites W3104328056 @default.
• W4313201977 cites W3117396456 @default.
• W4313201977 cites W3156258501 @default.
• W4313201977 cites W3162195278 @default.
• W4313201977 cites W3163043804 @default.
• W4313201977 cites W3183989082 @default.
• W4313201977 cites W3193614870 @default.
• W4313201977 cites W3194570774 @default.
• W4313201977 cites W3200223380 @default.
• W4313201977 cites W4200304200 @default.
• W4313201977 cites W4200434820 @default.
• W4313201977 cites W4211012816 @default.
• W4313201977 cites W4214943375 @default.
• W4313201977 cites W4225526112 @default.
• W4313201977 cites W4289203456 @default.
• W4313201977 cites W4289778922 @default.
• W4313201977 cites W4290633377 @default.
• W4313201977 cites W4293223349 @default.
• W4313201977 cites W4293223889 @default.
• W4313201977 doi "https://doi.org/10.1016/j.ejim.2022.12.008" @default.
• W4313201977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36575107" @default.
• W4313201977 hasPublicationYear "2023" @default.
• W4313201977 type Work @default.
• W4313201977 citedByCount "6" @default.
• W4313201977 countsByYear W43132019772023 @default.
• W4313201977 crossrefType "journal-article" @default.
• W4313201977 hasAuthorship W4313201977A5002872853 @default.
• W4313201977 hasAuthorship W4313201977A5010470244 @default.
• W4313201977 hasAuthorship W4313201977A5015687443 @default.
• W4313201977 hasAuthorship W4313201977A5033442682 @default.
• W4313201977 hasAuthorship W4313201977A5034263662 @default.
• W4313201977 hasAuthorship W4313201977A5037695205 @default.
• W4313201977 hasAuthorship W4313201977A5039638412 @default.
• W4313201977 hasAuthorship W4313201977A5046431472 @default.
• W4313201977 hasAuthorship W4313201977A5046904043 @default.
• W4313201977 hasAuthorship W4313201977A5051587096 @default.
• W4313201977 hasAuthorship W4313201977A5063343500 @default.
• W4313201977 hasAuthorship W4313201977A5088161654 @default.
• W4313201977 hasBestOaLocation W43132019771 @default.

• next