FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313202089> ?p ?o ?g. }

• W4313202089 endingPage "e00778" @default.
• W4313202089 startingPage "e00778" @default.
• W4313202089 abstract "Sunburn is one of the most common skin lesions caused by excessive UV exposure, and its incidence is highly correlated with the risks of skin cancer. A variety of drugs including corticosteroids and NSAIDs have been developed to treat acute sunburn, however, they have raised severe concerns such as poor healing efficacy and long recovery time. We have for the first time extracted non-denatured type I collagen from yak hide, which displays a canonical triple helical structure with melting temperature of 42.7 °C. The highly pure yak collagen type I (YCI) self-assembles to form well-ordered nanofibers with periodic d-bands. YCI is highly biocompatible, and it significantly promotes the proliferation and adhesion of HFF-1 cells. The sunburn healing effects of YCI has been investigated using acute skin injury mouse model. Histological analysis shows that 4 days’ treatment of YCI has resulted in the recovery of sunburned mice skin to a healthy state, indicated by pronounced acceleration of epithelization and collagen deposition. The collagen volume fraction as well as the hydroxyproline (Hyp) content of YCI-treated sunburned skin have been found to be greatly increased, confirming the enhanced regeneration of collagen. YCI creams and dressings have also shown superior healing capacity of sunburn by remarkably shortening the recovery time. Notably, the denatured collagen-targeted staining results indicated a large quantity of denatured collagen in sunburned mice, which became substantially reduced after the YCI treatment. FITC-labeled YCI has been further found to penetrate into the dermis of sunburned mice. The highly biocompatible and bioactive non-denatured YCI provides an improved treatment of sunburn, indicating very promising applications of YCI in cosmetics and dermatology." @default.
• W4313202089 created "2023-01-06" @default.
• W4313202089 creator A5029917070 @default.
• W4313202089 creator A5037796884 @default.
• W4313202089 creator A5067346510 @default.
• W4313202089 creator A5072234105 @default.
• W4313202089 creator A5074519587 @default.
• W4313202089 creator A5082245868 @default.
• W4313202089 date "2023-03-01" @default.
• W4313202089 modified "2023-10-14" @default.
• W4313202089 title "Non-denatured yak type I collagen accelerates sunburned skin healing by stimulating and replenishing dermal collagen" @default.
• W4313202089 cites W1728722352 @default.
• W4313202089 cites W1972229031 @default.
• W4313202089 cites W1973759941 @default.
• W4313202089 cites W1980390007 @default.
• W4313202089 cites W1993614351 @default.
• W4313202089 cites W1999494338 @default.
• W4313202089 cites W2016206284 @default.
• W4313202089 cites W2021521727 @default.
• W4313202089 cites W2022642929 @default.
• W4313202089 cites W2024976587 @default.
• W4313202089 cites W2029390954 @default.
• W4313202089 cites W2034150300 @default.
• W4313202089 cites W2041457752 @default.
• W4313202089 cites W2048104669 @default.
• W4313202089 cites W2049152587 @default.
• W4313202089 cites W2062252192 @default.
• W4313202089 cites W2067306452 @default.
• W4313202089 cites W2103797279 @default.
• W4313202089 cites W2114655963 @default.
• W4313202089 cites W2139780766 @default.
• W4313202089 cites W2139821685 @default.
• W4313202089 cites W2144401631 @default.
• W4313202089 cites W2149716668 @default.
• W4313202089 cites W2150172794 @default.
• W4313202089 cites W2171764430 @default.
• W4313202089 cites W2231675245 @default.
• W4313202089 cites W2281810024 @default.
• W4313202089 cites W2409198500 @default.
• W4313202089 cites W2476542314 @default.
• W4313202089 cites W2515753121 @default.
• W4313202089 cites W2574108460 @default.
• W4313202089 cites W2639157042 @default.
• W4313202089 cites W2739342094 @default.
• W4313202089 cites W2747118295 @default.
• W4313202089 cites W28882650 @default.
• W4313202089 cites W2911924212 @default.
• W4313202089 cites W2914897010 @default.
• W4313202089 cites W2997669810 @default.
• W4313202089 cites W3013903911 @default.
• W4313202089 cites W3047183405 @default.
• W4313202089 cites W3089289366 @default.
• W4313202089 cites W3115678150 @default.
• W4313202089 cites W3199284680 @default.
• W4313202089 cites W4211212071 @default.
• W4313202089 cites W56608080 @default.
• W4313202089 doi "https://doi.org/10.1016/j.btre.2022.e00778" @default.
• W4313202089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36578365" @default.
• W4313202089 hasPublicationYear "2023" @default.
• W4313202089 type Work @default.
• W4313202089 citedByCount "2" @default.
• W4313202089 countsByYear W43132020892023 @default.
• W4313202089 crossrefType "journal-article" @default.
• W4313202089 hasAuthorship W4313202089A5029917070 @default.
• W4313202089 hasAuthorship W4313202089A5037796884 @default.
• W4313202089 hasAuthorship W4313202089A5067346510 @default.
• W4313202089 hasAuthorship W4313202089A5072234105 @default.
• W4313202089 hasAuthorship W4313202089A5074519587 @default.
• W4313202089 hasAuthorship W4313202089A5082245868 @default.
• W4313202089 hasBestOaLocation W43132020891 @default.
• W4313202089 hasConcept C142724271 @default.
• W4313202089 hasConcept C153911025 @default.
• W4313202089 hasConcept C16005928 @default.
• W4313202089 hasConcept C185592680 @default.
• W4313202089 hasConcept C189165786 @default.
• W4313202089 hasConcept C190567982 @default.
• W4313202089 hasConcept C203014093 @default.
• W4313202089 hasConcept C2777524492 @default.
• W4313202089 hasConcept C2777624698 @default.
• W4313202089 hasConcept C2779797417 @default.
• W4313202089 hasConcept C2780269544 @default.
• W4313202089 hasConcept C2780644872 @default.
• W4313202089 hasConcept C55493867 @default.
• W4313202089 hasConcept C71924100 @default.
• W4313202089 hasConcept C86803240 @default.
• W4313202089 hasConceptScore W4313202089C142724271 @default.
• W4313202089 hasConceptScore W4313202089C153911025 @default.
• W4313202089 hasConceptScore W4313202089C16005928 @default.
• W4313202089 hasConceptScore W4313202089C185592680 @default.
• W4313202089 hasConceptScore W4313202089C189165786 @default.
• W4313202089 hasConceptScore W4313202089C190567982 @default.
• W4313202089 hasConceptScore W4313202089C203014093 @default.
• W4313202089 hasConceptScore W4313202089C2777524492 @default.
• W4313202089 hasConceptScore W4313202089C2777624698 @default.
• W4313202089 hasConceptScore W4313202089C2779797417 @default.
• W4313202089 hasConceptScore W4313202089C2780269544 @default.
• W4313202089 hasConceptScore W4313202089C2780644872 @default.
• W4313202089 hasConceptScore W4313202089C55493867 @default.

• next