Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313203881> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W4313203881 endingPage "63" @default.
- W4313203881 startingPage "54" @default.
- W4313203881 abstract "Pollution with heavy metal salts is an important environmental problem today, having an adverse effect on public health. The endocrine system maintains homeostasis in the body. The purpose of the work is to study the morphological changes of the cerebellar cortex and epiphyses of sexually mature male rats under the condition of long-term exposure to the body of a complex of heavy metal salts. The morphological changes in the cerebellar cortex and epiphysis of sexually mature male rats under the condition of long-term exposure to heavy metal salts was studied. Animals of the experimental group were simulated microelementosis by adding to drinking water a mixture of heavy metal salts for 60 days: zinc (ZnSO4×7H2O) – 5 mg/l, copper (CuSO4×5H2O) – 1 mg/l, iron (FeSO4) – 10 mg/l, manganese (MnSO4×5H2O) – 0.1 mg/l, lead (Pb(NO3)2) – 0.1 mg/l and chromium (K2Cr2O7) – 0.1 mg/l. Morphological, morphometric and statistical research methods were used. Long-term (60-days) intake of heavy metal salts mixture in the body of experimental animals leads to the development of the general adaptation syndrome, the stage of chronic stress “subcompensation” in the pineal gland. Morphological changes in the organs had a nonspecific polymorphic character, such as a sharp violation of hemodynamics, a violation of the morphology of the vascular wall, the state of pinealocytes and Purkinje cells, the development of tissue hypoxia, processes of apoptosis and reactive astrogliosis as a response to the action of a damaging agent. The pineal gland of the experimental animals showed signs of indole production, but the evacuation of hormones (including melatonin) into the vascular bed was hampered due to the violation of the morphology of the vascular wall and the cell membrane of pinealocytes. This led to a deficiency of this hormone in the body of the experimental animals, which negatively affected the adaptive processes in the cerebellar cortex in response to the action of the stress agent. Compensatory and adaptive processes in the pineal gland and cerebellar cortex had signs of functional stress. Adaptive processes were observed both in a small number of pinealocytes and in Purkinje cells, as well as an active adaptive glial reaction in both organs." @default.
- W4313203881 created "2023-01-06" @default.
- W4313203881 creator A5005226538 @default.
- W4313203881 creator A5036864559 @default.
- W4313203881 creator A5047132830 @default.
- W4313203881 creator A5057276899 @default.
- W4313203881 date "2022-12-24" @default.
- W4313203881 modified "2023-09-26" @default.
- W4313203881 title "Morphological changes of sexually mature rat's pineal gland and cerebellar cortex under long-term exposure to heavy metal salts" @default.
- W4313203881 cites W1530782517 @default.
- W4313203881 cites W1965140390 @default.
- W4313203881 cites W1973703381 @default.
- W4313203881 cites W1977256540 @default.
- W4313203881 cites W2005450121 @default.
- W4313203881 cites W2039898634 @default.
- W4313203881 cites W2059594432 @default.
- W4313203881 cites W2096516727 @default.
- W4313203881 cites W2101837018 @default.
- W4313203881 cites W2139474809 @default.
- W4313203881 cites W2146053732 @default.
- W4313203881 cites W2157555067 @default.
- W4313203881 cites W2171722927 @default.
- W4313203881 cites W2526369182 @default.
- W4313203881 cites W2756354805 @default.
- W4313203881 cites W2774593488 @default.
- W4313203881 cites W3181229382 @default.
- W4313203881 doi "https://doi.org/10.31393/morphology-journal-2022-28(4)-08" @default.
- W4313203881 hasPublicationYear "2022" @default.
- W4313203881 type Work @default.
- W4313203881 citedByCount "0" @default.
- W4313203881 crossrefType "journal-article" @default.
- W4313203881 hasAuthorship W4313203881A5005226538 @default.
- W4313203881 hasAuthorship W4313203881A5036864559 @default.
- W4313203881 hasAuthorship W4313203881A5047132830 @default.
- W4313203881 hasAuthorship W4313203881A5057276899 @default.
- W4313203881 hasBestOaLocation W43132038811 @default.
- W4313203881 hasConcept C121446783 @default.
- W4313203881 hasConcept C126322002 @default.
- W4313203881 hasConcept C134018914 @default.
- W4313203881 hasConcept C169760540 @default.
- W4313203881 hasConcept C178790620 @default.
- W4313203881 hasConcept C185592680 @default.
- W4313203881 hasConcept C2777348757 @default.
- W4313203881 hasConcept C2779652256 @default.
- W4313203881 hasConcept C2780059843 @default.
- W4313203881 hasConcept C2992333117 @default.
- W4313203881 hasConcept C535196362 @default.
- W4313203881 hasConcept C544153396 @default.
- W4313203881 hasConcept C63645605 @default.
- W4313203881 hasConcept C71924100 @default.
- W4313203881 hasConcept C86803240 @default.
- W4313203881 hasConceptScore W4313203881C121446783 @default.
- W4313203881 hasConceptScore W4313203881C126322002 @default.
- W4313203881 hasConceptScore W4313203881C134018914 @default.
- W4313203881 hasConceptScore W4313203881C169760540 @default.
- W4313203881 hasConceptScore W4313203881C178790620 @default.
- W4313203881 hasConceptScore W4313203881C185592680 @default.
- W4313203881 hasConceptScore W4313203881C2777348757 @default.
- W4313203881 hasConceptScore W4313203881C2779652256 @default.
- W4313203881 hasConceptScore W4313203881C2780059843 @default.
- W4313203881 hasConceptScore W4313203881C2992333117 @default.
- W4313203881 hasConceptScore W4313203881C535196362 @default.
- W4313203881 hasConceptScore W4313203881C544153396 @default.
- W4313203881 hasConceptScore W4313203881C63645605 @default.
- W4313203881 hasConceptScore W4313203881C71924100 @default.
- W4313203881 hasConceptScore W4313203881C86803240 @default.
- W4313203881 hasIssue "4" @default.
- W4313203881 hasLocation W43132038811 @default.
- W4313203881 hasOpenAccess W4313203881 @default.
- W4313203881 hasPrimaryLocation W43132038811 @default.
- W4313203881 hasRelatedWork W1990144626 @default.
- W4313203881 hasRelatedWork W2008170720 @default.
- W4313203881 hasRelatedWork W2008541300 @default.
- W4313203881 hasRelatedWork W2017830665 @default.
- W4313203881 hasRelatedWork W2023258720 @default.
- W4313203881 hasRelatedWork W2050416457 @default.
- W4313203881 hasRelatedWork W2075463443 @default.
- W4313203881 hasRelatedWork W2081213711 @default.
- W4313203881 hasRelatedWork W2092305624 @default.
- W4313203881 hasRelatedWork W2174804681 @default.
- W4313203881 hasVolume "28" @default.
- W4313203881 isParatext "false" @default.
- W4313203881 isRetracted "false" @default.
- W4313203881 workType "article" @default.