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- W4313204055 abstract "Leclercia adecarboxylata is a recently acknowledged emerging pathogen. It is a member of the Enterobacterals family, formerly thought to be a member of the genus Escherichia. Isolation was reported from various animal and environmental specimens. However, it rarely causes infection in humans, and the true frequency is unknown or underestimated. Leclercia adecarboxylata showed an ascending resistance grade from pan-sensitive to Carbapenem-resistant due to its ability to produce and harbour hydrolysing enzymes that challenge daily clinical practices. In our report, the isolate was misidentified as Citrobacter koseri by Analytical Profile Index for Enterobacterals (API E), and as Pantoea species by Vitek 2 but confirmed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and 16S ribosomal RNA analysis as Leclercia adecarboxylata. Conventional PCR revealed the presence of two populations of resistance genes, VIM-1 and OXA-48. Herein, a report of the first clinical emergence of Leclercia adecarboxylata producing VIM-1 in a rectal swab of a 63-year-old non-immunocompromised female with acute intracerebral haemorrhage." @default.
- W4313204055 created "2023-01-06" @default.
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- W4313204055 date "2023-03-01" @default.
- W4313204055 modified "2023-09-30" @default.
- W4313204055 title "First clinical case of VIM-1-producing Leclercia adecarboxylata: A case report and literature review" @default.
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- W4313204055 doi "https://doi.org/10.1016/j.medmic.2022.100075" @default.
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